Publications

Papers from the group, newest first. The first list shows those led by a group member; the second shows every paper the group has published. Code to reproduce selected papers is on GitHub, at CEMRG-publications.

Maximilian Balmus, Sheng‐Ya Wang, Edward W. G. Ashton, Rosie K. Barrows, Molly Monks, Yuzhang Ge, Arthur Lefebvre, Steven A. Niederer
In Silico Clinical Trials in Drug Development: Virtual Patients, Applications, and Regulatory Convergence
Clinical Pharmacology & Therapeutics, 2026
Neil Bodagh, Vinush Vigneswaran, Ali Gharaviri, Irum Kotadia, Magda Klis, …, Steven Niederer, …
Atrial fibrillation phenotypes derived from multimodal data exhibit distinct electrophysiological substrate characteristics, symptom trajectories, and ablation outcomes
European Heart Journal Open, 2026
P.J. Luthert, L. Faes, A.J. Foss, D.J. Fu, L.J. Hill, …, S. Niederer, …
The Virtual Eye: An integrative multiscale framework for mechanistic modelling of ocular physiology and disease
Progress in Retinal and Eye Research, 2026
Nikki van Pouderoijen, Luuk H.G.A. Hopman, Melati Post, Joris R. de Groot, Cassia Kessler-Iglesias, …, Steven A. Niederer, …
Right Atrial Cardiomyopathy Assessed by Late Gadolinium Enhancement Cardiac MRI Following Pulmonary Vein Isolation in Patients with Atrial Fibrillation
Heart Rhythm, 2026
Olivier Bernard, William A. Romero R., Cyprien Bouton, Celia Goujat, Hang Jung Ling, …, Abdul Qayyum, …, Steven A. Niederer, …
The MYOSAIQ Challenge: Myocardial Segmentation with Automated Infarct Quantification
The Journal of Machine Learning for Biomedical Imaging, 2026
Radka Jersakova, Sam F. Greenbury, Ed Chalstrey, Edwin Brown, Marjan Famili, …, Max Balmus, …, Steve Niederer, …
AutoEmulate: A PyTorch tool for end-to-end emulation workflows
The Journal of Open Source Software, 2026
Shuang Qian, Devran Ugurlu, Elliot Fairweather, Richard E. Jones, Hassan Zaidi, Sanjay Prasad, Brian P. Halliday, …, Cristobal Rodero, Abdul Qayyum, …, Martin Bishop, Steven Niederer
In silico trials for sex-specific patient inclusion criteria in cardiac resynchronization therapy
npj Digital Medicine, 2026
Cristobal Rodero, Lara Curran, Christopher W. Lanyon, Paolo Inglese, Abdul Qayyum, Rosie K. Barrows, Jose A. Solis-Lemus, Shahrokh Rahmani, Marina Strocchi, Angela W.C. Lee, Tiffany M.G. Baptiste, Ludovica Cicci, Edward Burford, Elias Karabelas, …, Steven A. Niederer
Computational models show that functional remodeling, not anatomy, reshapes physiological determinants of cardiac performance in hypertrophic cardiomyopathy
Journal of Molecular and Cellular Cardiology, 2026
Vishal Mehta, Nadeev Wijesuriya, Felicity De Vere, Sandra Howell, Mark K Elliott, …, Steven A Niederer, …
Redefining response to cardiac resynchronization therapy: a post hoc analysis of the MORE-CRT MPP trial
EP Europace, 2026
Christopher Burr, Steven Niederer, David Wagg
Digital Well-Being in an Age of AI-Enabled Digital Twins
Routledge eBooks, 2026
Shambhavi Malik, Ludovica Cicci, Abdul Qayyum, Rahul Ghelani, Ji-jian Chow, Jagdeep Singh Mohal, Zachary I. Whinnett, …, Steven A. Niederer
Body surface potential driven personalisation of electrophysiological digital twins in hypertrophic cardiomyopathy
PLoS Computational Biology, 2026
Aditi Kulkarni, Rosie K. Barrows, Angela W.C. Lee, Caroline H. Roney, Marina Strocchi, Edward J. Vigmond, Gernot Plank, Nicholas Panay, Steven A. Niederer
Multiscale modelling of hormonal effects on atrial fibrillation in female physiology
The Journal of Precision Medicine Health and Disease, 2026
Kaiyuan Yang, Fabio Musio, Yihui Ma, Norman Juchler, Johannes C. Paetzold, …, Abdul Qayyum, …, Steven Niederer, …
The TopCoW Challenge — Topology-Aware Circle of Willis Segmentation for CT and MR Angiography
NEJM AI, 2026
Muhammad Imran, Jonathan R. Krebs, Vishal Balaji Sivaraman, Teng Zhang, Amarjeet Kumar, …, Abdul Qayyum, …, Steven A. Niederer, …
Multi-class segmentation of aortic branches and zones in computed tomography angiography: The AortaSeg24 challenge
Medical Image Analysis, 2026
Xichong Liu, Abdul Qayyum, Sabyasachi Bandyopadhyay, Sulaiman Somani, Prasanth Ganesan, Rayan A. Ansari, …, Steven Niederer, …
Identifying the Presence and Characteristics of Mid-Myocardial and Epicardial Fibrosis From Intracardiac Electrograms in Patients Undergoing Ventricular Arrhythmia Ablation Using a Transformer-Based Self-Supervised Classifier
Circulation Arrhythmia and Electrophysiology, 2026
Fay Frost, Maximilian Balmus, Levan Bokeria, Joe Longbottom, Camila Rangel-Smith, Harry Saxton, …, Steve Niederer, …
Rapid personalisation of cardiovascular models using invasively measured right ventricular pressure
Computers in Biology and Medicine, 2026
Mahmoud Ehnesh, Haseeb Valli, Ovais A. Jaffery, Sam Coveney, Alexander Zolotarev, …, Steven A. Niederer, …, Caroline Roney
Comparative multimodal calibration of patient‐specific atrial fibrillation models: Impact of imaging and electrophysiology data on arrhythmogenic substrate identification
The Journal of Physiology, 2026
José Alonso Solís-Lemus, Rosie K. Barrows, Cristobal Rodero, Marina Strocchi, Natalie Montarello, Nishant Lahoti, Cesare Corrado, Abdul Qayyum, Shahrokh Rahmani, Caroline Roney, Gernot Plank, Christoph Augustin, …, Steven A. Niederer
Assessing the importance of sex and disease-specific anatomy in electrophysiology and mechanical simulations with a newly developed public virtual cohort of four-chamber heart models
PLoS Computational Biology, 2026
A Liew, N Wijesuriya, S Howell, F Devere, J Whitaker, S Niederer, …
Comparable acute hemodynamic effects of left bundle branch pacing delivered from the right and left ventricular septum
EP Europace, 2026
A Liew, N Wijesuriya, S Howell, F Devere, J Whitaker, S Niederer, …
Comparing the acute biventricular hemodynamic effects of left bundle branch area pacing (LBBAP) and left bundle optimized cardiac resynchronization therapy (LOT-CRT)
EP Europace, 2026
M Klis, N Bodagh, V Vigneswaran, A Von Kietzell, A Gharaviri, …, S Niederer, …
Coronary CT assessment of left atrial remodeling in hypertrophic cardiomyopathy reveals selective lateral wall thickening
EP Europace, 2026
N Bodagh, V Vigneswaran, A Gharaviri, I Kotadia, M Klis, S Niederer, …
Impact of raised body mass index on bi-atrial structure, function, and electrophysiology in patients with atrial fibrillation
EP Europace, 2026
A Liew, N Wijesuriya, S Howell, F Devere, J Whitaker, S Niederer, …
Invasive assessment of right ventricular activation patterns with left bundle branch area pacing (LBBAP) and left bundle optimized cardiac resynchronization therapy (LOT-CRT)
EP Europace, 2026
F De Vere, M Strocchi, T Baptiste, A Lefebvre, N Wijesuriya, S Howell, A Liew, S Niederer, A Rinaldi
Mechanistic insights into the importance of restoring atrioventricular synchrony in dyssynchronous heart failure patients with atrial fibrillation
EP Europace, 2026
Mohammad Kayyali, Ana Mincholé, Martin Bishop, Hassan Zaidi, Shuang Qian, Steven Niederer, Rachel Bastiaenen, Chris Miles, Pablo Lamata, …
Posterior Electrical Axis Deviation Is Associated With Future Development of Left Bundle Branch Block
JACC Advances, 2026
N Van Pouderoijen, L H G A Hopman, M Post, J R De Groot, C Kessler-Iglesias, …, S A Niederer, …
Right atrial remodeling following pulmonary vein isolation in patients with atrial fibrillation assessed by late gadolinium enhancement cardiac MRI
EP Europace, 2026
N Bodagh, V Vigneswaran, A Gharaviri, I Kotadia, M Klis, …, S Niederer, …
Sex-based differences in bi-atrial structure, function, and electrophysiology in atrial fibrillation
EP Europace, 2026
S Howell, T Hamakarim, J Yu, S Mangal, V Edem, …, S Niederer, …
Similar incidence of PICM in patients with preserved and moderate range ejection fraction
EP Europace, 2026
C Corrado, C H Roney, S M Narayan, W R Giles, S A Niederer
The effects of alterations of plasma electrolytes on post-repolarisation refractoriness
EP Europace, 2026
N Bodagh, V Vigneswaran, A Gharaviri, I Kotadia, M Klis, …, S Niederer, …
Unsupervised machine learning of multimodal data to identify atrial fibrillation subgroups likely to benefit from pulmonary vein isolation
EP Europace, 2026
Vitaliy Androshchuk, Edouard Long, Charles Sillett, Omar Chehab, Natalie Montarello, Joshua Wilcox, Marina Strocchi, …, Steven Niederer, …
Multi-chamber three-dimensional myocardial strain assessment by computed tomography: a comparison with speckle tracking echocardiography and association with pulmonary hypertension in severe aortic stenosis
Frontiers in Cardiovascular Medicine, 2026
Jia Fu, Litingyu Wang, He Li, Zihao Luo, Huamin Wang, …, Abdul Qayyum, …, Steven A. Niederer, …
SegRap2025: A benchmark of gross tumor volume and lymph node clinical target volume Segmentation for Radiotherapy Planning of nasopharyngeal carcinoma
Medical Image Analysis, 2026
Luca Soattin, Leila Topal, Roman Tikhomirov, Daniele Lagomarsino-Oneto, Sami Al-Othman, Angela W C Lee, …, Steven A Niederer, …
Endurance exercise remodels pulmonary vein sleeve myocytes and promotes a proarrhythmic atrial substrate
European Heart Journal, 2026
Yu Deng, Yiyang Xu, Linglong Qian, Charlène Mauger, Anastasia Nasopoulou, …, Steven Niederer, …
MorphiNet: A Graph Subdivision Network for Adaptive Bi-Ventricle Surface Reconstruction
IEEE Transactions on Medical Imaging, 2026
Nikki van Pouderoijen, Cassia Kessler-Iglesias, Andrew Jabbour, Cornelis P. Allaart, Steven A. Niederer, Diane Fatkin, …
Quantification of left and right atrial late gadolinium enhancement using different methods in healthy individuals
Heart Rhythm, 2026
Angela W.C. Lee, Marina Strocchi, Alphonsus Liew, Sandra Howell, Felicity De Vere, Nadeev Wijesuriya, …, Steven Niederer
Computational analysis of intracardiac collision risk and optimal site for right ventricular leadless left bundle branch area pacing: A simulation study
Heart Rhythm O2, 2026
C. Shen, M. Zhang, H. Keramati, S. Zhang, R. Gharleghi, J. J. Wentzel, …, A. Qayyum, S. A. Niederer, …
The Anatomy of Coronary Risk: How Arterial Geometry Shapes Coronary Artery Disease Through Blood Flow Haemodynamics – Latest Methods, Insights and Clinical Implications
Archives of Computational Methods in Engineering, 2026
Abdul Qayyum, Moona Mazher, M. K. A. Ahamed Khan, Ridzuan A., Mastaneh Mokayef, …, Steven Niederer
Deep Spatiotemporal Convolutional Network for Brain Reperfusion Prediction using Multiphase Computed Tomographic Angiography and Clinical Data
WSEAS Transactions on Signal Processing archive, 2026
Mariya Mamajiwala, Cesare Corrado, Christopher W. Lanyon, Steven A. Niederer, Richard D. Wilkinson, Richard H. Clayton
Rapid calibration of atrial electrophysiology models using Gaussian process emulators in the ensemble Kalman filter
Scientific Reports, 2026
Steven A Niederer, Maximilian Balmus, Christopher Burr, Timothy J A Chico, Richard H Clayton, Wenjia Bai, …, Sheng-Ya Wang, …
Digital twins for cardiopulmonary medicine: the case for pulmonary arterial hypertension
American Journal of Respiratory and Critical Care Medicine, 2026
Louisa O’Neill, Keeran Vickneson, Ali Gharaviri, Iain Sim, Daniel O’Hare, …, Steven Niederer, …
Evaluation of bi-atrial dynamic electrophysiological properties in atrial septal defect patients
Frontiers in Physiology, 2026
Christopher David Burr, Shuang Qian, Peter Winter, Tim Chico, Camila Rangel Smith, David Wagg, Steven Alexander Niederer
Realising the digital twin: a thematic review and analysis of the ethical, legal, and social issues for digital twins in healthcare
AI & Society, 2026
Alexandre Lewalle, Gregory Milburn, Jania Bell, Kenneth S. Campbell, Steven A. Niederer
Human atrial skinned muscle fibers exhibit reduced length-dependent activation but show faster force development kinetics than ventricular muscle
Journal of Molecular and Cellular Cardiology, 2026
Holly Morgan, Amedeo Chiribiri, Marina Strocchi, Hassan Zaidi, Nathan C.K. Wong, Azizah Ardinal, Mark Elliott, Steven Niederer, …, Martin Bishop, …
Ischemia modulation via coronary revascularization and effects on the arrhythmic substrate
Heart Rhythm, 2026
Adelisa Avezzú, Stefano Longobardi, Anita Alvarez-Laviada, Francisca Schultz, Julia Gorelik, Catherine Williamson, Steven A. Niederer
A model for the human fetal ventricular myocyte electrophysiology
PLoS Computational Biology, 2026
Bei Zhou, Maximilian Balmus, Cesare Corrado, Ludovica Cicci, Shuang Qian, Steven A. Niederer
TorchCor: High-performance cardiac electrophysiology simulations with the finite element method on GPUs
SoftwareX, 2026
Vladyslav Zalevskyi, Thomas Sanchez, Misha Kaandorp, Margaux Roulet, Diego Fajardo-Rojas, …, Abdul Qayyum, …, Steven A. Niederer, …
Advances in automated fetal brain MRI segmentation and biometry: Insights from the FeTA 2024 challenge
Medical Image Analysis, 2026
Alphonsus C. Liew, Nadeev Wijesuriya, Felicity de Vere, Sandra Howell, Vishal Mehta, Steven Niederer, …
Laser vs rotational transvenous lead extraction: A systematic review and meta-analysis of procedural safety and efficacy outcomes
Heart Rhythm O2, 2026
Abdul Qayyum, Moona Mazher, Steven A. Niederer
AortaST: A Student-Teacher Framework for Multi-class Aortic Segmentation
Lecture notes in computer science, 2026
Abdul Qayyum, Moona Mazher, Steven A Niederer
CardioSeqM: A Scalable and Context-Aware Model for Unified Heart Segmentation from Volumetric Cardiac Data
Lecture notes in computer science, 2026
Abdul Qayyum, Moona Mazher, Steven A Niederer
Exploring Foundation Model Adaptations for 3D Medical Imaging: Prompt-Based Segmentation with xLSTM Network
Lecture notes in computer science, 2026
Moona Mazher, Steven A. Niederer, Abdul Qayyum
HectoMixNet: Advancing Automated Head and Neck Tumor Segmentation with Multicenter PET/CT Data
Lecture notes in computer science, 2026
Moona Mazher, Steven A. Niederer, Abdul Qayyum
NeuroNetMix: A 3D Encoder-Decoder with Quasiseparable Mixing for Robust Lesion Segmentation in Traumatic Brain Injury
Lecture notes in computer science, 2026
Abdul Qayyum, Moona Mazher, Muhammad Yamin, Steven A. Niederer
UniSeg-CT: A Foundation Model for Medical Image Segmentation across Cardiac, Oncologic, and Neurovascular Applications
Lecture notes in electrical engineering, 2026
Tiffany M. G. Baptiste, Rosie K. Barrows, Cristobal Rodero, Steven A. Niederer
Testing Treatments Virtually: How Digital Hearts can Save Lives
Frontiers for Young Minds, 2025
Nadeev Wijesuriya, Helena Lytton Cobbold, Keisha Kellman, Nikolaos Vogiatzakis, Felicity De Vere, …, Steven A. Niederer, …
Safety Outcomes of Hybrid Open Chest Transvenous Lead Extraction: A Multicenter Experience
Pacing and Clinical Electrophysiology, 2025
Caterina Vidal Horrach, Sam Coveney, Ovais Ahmed Jaffery, Mahmoud Ehnesh, Steven Niederer, Shohreh Honarbakhsh, …, Caroline H. Roney
Automated workflow to Integrate Electroanatomic Maps into Patient-Specific Bi-atrial Models For Personalized AF Treatment
Computing in cardiology, 2025
Mariya Mamajiwala, Cesare Corrado, Steven Niederer, Richard Wilkinson, Richard H. Clayton
Ensemble Kalman Filtering Based Calibration of Tissue Parameters Using Emulators of Left Atrial Electrophysiology Models
Computing in cardiology, 2025
Caterina Vidal Horrach, Laura Bevis, Mahmoud Ehnesh, Semhar Biniam Misghina, Ovais Ahmed Jaffery, …, Steven Niederer, …, Caroline H. Roney
Scalable Construction of Anatomically Detailed Biatrial Models with Personalised Electrophysiology from Imaging or Electroanatomic Mapping Data
Computing in cardiology, 2025
Semhar Biniam Misghina, Alexander М. Zolotarev, Elisa Rauseo, Carlos Edgar Lopez Barrera, Steven Niederer, Gregory Slabaugh, …, Caroline H. Roney
Towards Personalised Therapy in Atrial Fibrillation: The Role of Patient-Specific Fibrosis
Computing in cardiology, 2025
Cesare Corrado, Caroline H. Roney, Sanjiv M. Narayan, Wayne R. Giles, Steven A. Niederer
The effect of clinically relevant changes in extracellular electrolyte concentrations on human atrial arrhythmias
Communications Medicine, 2025
Kang Wang, Chen Qin, Zhang Shi, Haoran Wang, Xiwen Zhang, …, Abdul Qayyum, …, Steven A. Niederer, …
Extreme cardiac MRI analysis under respiratory motion: Results of the CMRxMotion challenge
Medical Image Analysis, 2025
Christopher W Lanyon, Cristobal Rodero, Abdul Qayyum, Tiffany MG Baptiste, Steven A Niederer, Richard D Wilkinson
Weaving the Digital Tapestry: Methods for Emulating Cohorts of Cardiac Digital Twins Using Gaussian Processes
Annals of Biomedical Engineering, 2025
Ovais Ahmed Jaffery, Carlos E Lopez-Barrera, Cristobal Rodero, Alexander M Zolotarev, Wilson W Good, Gregory Slabaugh, Steven Niederer, …, Caroline H Roney
Automated generation of ablation lesion masks: a unison of electro and optic flow mapping for persistent AF virtual cohorts
EP Europace, 2025
Tiffany M.G. Baptiste, Cristobal Rodero, Charles P. Sillett, Marina Strocchi, Christopher W. Lanyon, Christoph M. Augustin, Angela W. C. Lee, José Alonso Solís-Lemus, Caroline H. Roney, Daniel B. Ennis, Ronak Rajani, …, Steven A. Niederer
Regional heterogeneity in left atrial stiffness impacts passive deformation in a cohort of patient-specific models
PLoS Computational Biology, 2025
Alphonsus C. Liew, Vishal Mehta, Nadeev Wijesuriya, Sandra Howell, Felicity de Vere, Steven Niederer, …
Risk stratification in transvenous lead extraction: Current models and clinical applications
Heart Rhythm O2, 2025
S Misghina, A Zolotarev, E Rauseo, C E Barrera, S A Niederer, G Slabaugh, …, C H Roney
In-silico insights into the role of patient-specific fibrosis in personalised therapy selection for atrial fibrillation
European Heart Journal, 2025
Alphonsus Liew, Nadeev Wijesuriya, Sandra Howell, Felicity de Vere, Steven Niederer, Christopher Aldo Rinaldi
A review on the impact of cardiac pacing on right ventricular and tricuspid valve function
Expert Review of Medical Devices, 2025
Nadeev Wijesuriya, Felicity De Vere, Sandra Howell, Alphonsus Liew, Baldeep Sidhu, …, Steven A. Niederer, …
Efficacy of leadless left ventricular endocardial stimulation for non-responders to cardiac resynchronization therapy
Journal of Interventional Cardiac Electrophysiology, 2025
Alphonsus Liew, Marina Strocchi, Cristobal Rodero, Karli K. Gillette, Nadeev Wijesuriya, Sandra Howell, Felicity de Vere, …, Steven Niederer, …
Comparing the effects of left bundle branch pacing and leadless right ventricular pacing on intraventricular and interventricular dyssynchrony using in silico modelling
Frontiers in Physiology, 2025
Jack W. Samways, Timothy Cheng, Ji-Jian Chow, Matthew J. Shun-Shin, Nadine Ali, …, Marina Strocchi, Steven A. Niederer, …
Ventricular repolarization is improved by His resynchronization therapy but not biventricular pacing
Heart Rhythm, 2025
Neil Bodagh, Iain Sim, Mahta Haghighat Ghahfarokhi, Kyaw Soe Tun, Irum Kotadia, …, Jose Alonso Solis Lemus, …, Steven Niederer, …
Combining clinical and left atrial electromechanical remodelling data: potential to improve atrial fibrillation ablation outcome prediction
BMC Medical Informatics and Decision Making, 2025
Weitong Zhang, Mengyun Qiao, Chengqi Zang, Steven Niederer, Paul M. Matthews, Wenjia Bai, …
Multi-agent Reasoning for Cardiovascular Imaging Phenotype Analysis
Lecture notes in computer science, 2025
Meritxell Riera-Marín, Sikha O.K., Júlia Rodríguez-Comas, Matthias Stefan May, Zhaohong Pan, …, Abdul Qayyum, …, Steven A. Niederer, …
Calibration and Uncertainty for multiRater Volume Assessment in multiorgan Segmentation (CURVAS) challenge results
Computers in Biology and Medicine, 2025
Sian Chivers, Nicolò Pini, Shayan Chowdhury, Ludovica Cicci, Trisha Vigneswaran, Vita Zidere, …, Stephen Niederer, …
Clinical Role of the Noninvasive Abdominal Fetal ECG in the Detection and Monitoring of Fetal Tachycardia
Circulation Arrhythmia and Electrophysiology, 2025
Thomas Grandits, Christoph M. Augustin, Gundolf Haase, Norbert Jost, Gary R. Mirams, Steven A. Niederer, …
Neural network emulation of the human ventricular cardiomyocyte action potential: A promising tool for more efficient computations in quantitative systems pharmacology studies
Journal of Pharmacological and Toxicological Methods, 2025
S Samaneh Lashkarinia, Angela W C Lee, Tiffany M G Baptiste, Rosie K Barrows, Charles P Sillett, Cristobal Rodero, Upasana Tayal, Antonio de Marvao, Nicholas Panay, Catherine Williamson, …, Marina Strocchi, Steven A Niederer
Representation of women in cardiovascular disease management: a systematic analysis of ESC guidelines
Open Heart, 2025
Marina Strocchi, Christoph M. Augustin, Matthias A. F. Gsell, Christopher A. Rinaldi, Edward J. Vigmond, …, Steven A. Niederer
Integrating Imaging and Invasive Pressure Data into a Multiscale Whole-Heart Model
Journal of Biomechanical Engineering, 2025
Charles Sillett, Vitaliy Androshchuk, Edouard Long, Tiffany M.G. Baptiste, Marina Strocchi, Jose Alonso Solis Lemus, Angela WC. Lee, Caroline H. Roney, Ronak Rajani, Tiffany Patterson, …, Steven A. Niederer
Three-dimensional left atrial strain from retrospective gated computed tomography: Comparison with speckle-tracking echocardiography in patients with aortic stenosis
Journal of cardiovascular computed tomography, 2025
Kevin Monteiro, Sam Nallaperuma-Herzberg, Martina Mason, Steve Niederer
Graph Convolutional Neural Networks to Model the Brain for Insomnia
Lecture notes in computer science, 2025
C Kessler Iglesias, J. Pouliopoulos, R. Johnson, N. Olsen, A. Lee, S. Niederer, C. Hayward, …
Atrial Structure and Function in Subjects With DCM-Associated Truncating Titin Gene Variants
Heart Lung and Circulation, 2025
Nadeev Wijesuriya, Helen Sinabulya, Helena Johann‐Meyer, Keisha Kellman, Felicity de Vere, …, Steven A. Niederer, …
Joint Pacing and Vascular Intervention for the Management of Cardiac Device Associated Central Venous Obstruction
Pacing and Clinical Electrophysiology, 2025
Marina Strocchi, Daniel J. Hammersley, Brian P. Halliday, Sanjay K. Prasad, Steven A. Niederer
Cardiac digital twins: a tool to investigate the function and treatment of the diabetic heart
Cardiovascular Diabetology, 2025
Devran Ugurlu, Shuang Qian, Elliot Fairweather, Charlene Mauger, Bram Ruijsink, Laura Dal Toso, …, Marina Strocchi, …, Steven Niederer, Martin Bishop
Cardiac digital twins at scale from MRI: Open tools and representative models from ~ 55000 UK Biobank participants
PLoS ONE, 2025
Mohammad Kayyali, Ana Mincholé, Shuang Qian, Alistair Young, Devran Ugurlu, Elliot Fairweather, Steven Niederer, John Whitaker, Martin Bishop, …
Anatomical-electrical coupling of cardiac axes: Definitions and population variability for advancing personalised ECG interpretation
PLoS Computational Biology, 2025
Alexandre Lewalle, Tiffany M. G. Baptiste, Rosie K. Barrows, Ludovica Cicci, Cesare Corrado, Angela W. C. Lee, Cristobal Rodero, José Alonso Solís-Lemus, Marina Strocchi, Steven A. Niederer
Developing cardiac biomechanical models beyond the clinic: modeling stressors of daily life
Biomechanics and Modeling in Mechanobiology, 2025
José Marín, Tiffany M.G. Baptiste, Cristobal Rodero, Steven E. Williams, Steven A. Niederer, Ignacio García-Fernández
SciBlend: Advanced data visualization workflows within Blender
Computers & Graphics, 2025
Steven Niederer, Henry Chubb, Kenneth C. Bilchick, Christopher Aldo Rinaldi
Leadless and extravascular cardiac resynchronization therapy: the future for CRT?
Nature Reviews Cardiology, 2025
Aditi Kulkarni, Rosie K. Barrows, Marina Strocchi, Christoph M. Augustin, Matthias A. F. Gsell, Edward J. Vigmond, Gernot Plank, …, Steven A. Niederer
Influence of Oestrogen on Atrial Fibrillation Risk: An In-Silico Study
Functional Imaging and Modeling of the Heart, Lecture Notes in Computer Science, 2025
Angela W C Lee, Charles Sillett, José Alonso Solis-Lemus, Cassia Kessler Iglesias, Luuk H G A Hopman, Alina Hua, Peter Wheen, Abdul Qayyum, Marina Strocchi, Caroline Roney, …, Steven A Niederer
Is regional atrial strain a useful surrogate of regional atrial fibrosis in atrial cardiomyopathy?
European Heart Journal - Imaging Methods and Practice, 2025
Nadeev Wijesuriya, Marina Strocchi, Mark Elliott, Vishal Mehta, Felicity De Vere, Sandra Howell, …, Steven A. Niederer, …
Effect of leadless left ventricular endocardial and left bundle branch area pacing on biventricular repolarization metrics
Heart Rhythm, 2025
Shuang Qian, Devran Ugurlu, Elliot Fairweather, Laura Dal Toso, Yu Deng, Marina Strocchi, Ludovica Cicci, Richard E. Jones, Hassan Zaidi, …, Martin Bishop, Steven Niederer
Developing cardiac digital twin populations powered by machine learning provides electrophysiological insights in conduction and repolarization
Nature Cardiovascular Research, 2025
Alexander Jung, Christoph M. Augustin, Julia Voglhuber-Höller, Mara Kiessling, Senka Ljubojevic-Holzer, …, Steven A. Niederer, …
Computational modelling for improved translation of cardiac inotropic and lusitropic drug effects from rats to humans
Journal of Pharmacological and Toxicological Methods, 2025
Rosie K. Barrows, Christoph M. Augustin, Matthias A.F. Gsell, Caroline H. Roney, José A. Solís Lemus, Hao Xu, Alistair A. Young, …, Martin J. Bishop, …, Marina Strocchi, Steven A. Niederer
Rhythm control benefits left ventricular function compared with rate control in patients with atrial fibrillation: A computational study
Heart Rhythm O2, 2025
Marina Strocchi, Jack W Samways, Akriti Naraen, Nadine Ali, Matthew J Shun-Shin, …, Steven A Niederer
An in silico guide for ventriculo-ventricular delay programming for left bundle branch-optimized cardiac resynchronization therapy
EP Europace, 2025
Neil Bodagh, Kyaw Soe Tun, Adam Barton, Malihe Javidi, Darwon Rashid, …, Steven Niederer, …
GenECG: a synthetic image-based ECG dataset to augment artificial intelligence-enhanced algorithm development
BMJ Health & Care Informatics, 2025
Ali Gharaviri, Vinush Vigneswaran, Keeran Vickneson, Caroline Roney, Cesare Corrado, Sam Coveney, Kestutis Maciunas, …, Martin Bishop, Steven Niederer, …
Performance of atrial conduction velocity algorithms with error-prone clinical measurements for the identification of atrial fibrosis
Computers in Biology and Medicine, 2025
Martin A. Stoffel, Bryan M. Li, Kalle Westerling, Sophie Arana, Max Balmus, Eric Daub, Steve Niederer
AutoEmulate: A Python package for semi-automated emulation
The Journal of Open Source Software, 2025
Cristobal Rodero, Steven A. Niederer
Striking the balance: Complexity, simplicity, and credibility in mathematical biology
Proceedings of the National Academy of Sciences, 2025
Alphonsus Liew, Nadeev Wijesuriya, Sandra Howell, Felicity de Vere, Joshua Wilcox, …, Steven Niederer, …
Cardiac implantable electronic devices in the setting of tricuspid valve intervention: Risks, options, extraction and future perspectives: A state-of-the-art review
Heart Rhythm O2, 2025
Abdul Qayyum, Moona Mazher, Steven A. Niederer
A Two-Stage Self-Supervised Learning Framework for Automated Whole Heart Segmentation in CT and MRI: Addressing Challenges in Cardiac Imaging
Lecture notes in computer science, 2025
Abdul Qayyum, Moona Mazher, Steven A. Niederer
Assessing Self-supervised xLSTM-UNet Architectures for Head and Neck Tumor Segmentation in MR-Guided Applications
Lecture notes in computer science, 2025
Moona Mazher, Abdul Qayyum, Steven A. Niederer
Effective Approach Based on Student-Teacher Self-supervised Deep Learning for Multi-class Bi-atrial Segmentation Challenge
Lecture notes in computer science, 2025
Abdul Qayyum, Moona Mazher, Imran Razzak, Steven A. Niederer
Efficient Deep Learning Models for Evaluating the Progression of Age-Related Macular Degeneration Through Optical Coherence Tomography
Lecture notes in computer science, 2025
Abdul Qayyum, Moona Mazher, Steven A. Niederer
Efficient Deep Learning Models for Ultra-widefield Fundus Imaging for Diabetic Retinopathy
Lecture notes in computer science, 2025
Charles Sillett, Orod Razeghi, Tiffany M G Baptiste, Angela W C Lee, Jose Alonso Solis Lemus, Cristobal Rodero, Caroline H Roney, Ruibin Feng, Prasanth Ganesan, Hui Ju Chang, Paul Clopton, …, Steven A Niederer
Identification of atrial myopathy and atrial fibrillation recurrence after ablation using 3D left atrial phasic strain from retrospective gated computed tomography
European Heart Journal - Imaging Methods and Practice, 2025
Yiyang Xu, Hao Xu, Matthew Sinclair, Esther Puyol-Antón, Steven A. Niederer, Amedeo Chiribiri, …
Improved 3D Whole Heart Geometry from Sparse CMR Slices
Lecture notes in computer science, 2025
Marina Strocchi, Rosie K. Barrows, Cristobal Rodero, José Alonso Solís-Lemus, Shuang Qian, Ludovica Cicci, Abdul Qayyum, Devran Ugurlu, Christoph M. Augustin, Matthias A. F. Gsell, Edward J. Vigmond, Gernot Plank, Steven A. Niederer
Multi-scale Whole-Heart Electromechanics Modeling to Link Cellular, Tissue and Systemic Properties to Cardiac Biomarkers in the Diabetic Male and Female Heart
Lecture notes in computer science, 2025
David J Wagg, Christopher Burr, Jason Shepherd, Zack Xuereb Conti, Mark Enzer, Steven Niederer
The philosophical foundations of digital twinning
Data-Centric Engineering, 2025
Iain Sim, Jose Alonso Solis Lemus, Christopher O'Shea, Orod Razeghi, John Whitaker, Rahul Mukherjee, Daniel O'Hare, …, Caroline H. Roney, …, Steven Niederer, …
Quantification of atrial cardiomyopathy disease severity by electroanatomic voltage mapping and cardiac magnetic resonance imaging
Journal of Cardiovascular Electrophysiology, 2024
Mohammad Asjad, Abdul Qayyum, Moona Mazher, Usman Naseem, Tariq Khan, Steven Niederer, Imran Razzak
Federated Focal Modulated UNet for Cardiovascular Image Segmentation
IEEE International Conference on Big Data (BigData), 2024
Julia C. Isbister, Marina Strocchi, Matthew Riedy, Laura Yeates, Belinda Gray, Emma S. Singer, …, Steven A. Niederer, …
Noninvasive assessment of hydroquinidine effect in Brugada syndrome (QUIET BrS)
Heart Rhythm, 2024
Mohammad Kayyali, Ana Mincholé, Shuang Qian, Alistair Young, Devran Ugurlu, Elliot Fairweather, Steven Niederer, John Whitaker, Martin Bishop, …
Cardiac Anatomical and Electrical Axes: Proposed Definitions and Interplay
Computing in cardiology, 2024
Shahrokh Rahmani, Jim Pouliopoulos, Angela Lee, Rosie Kate Barrows, Marina Strocchi, Cristobal Rodero, Abdul Qayyum, Caroline H. Roney, Christoph Augustin, Gernot Plank, Andrew Jabbour, …, Steven Niederer
Cardiac Sensitivities to Biomechanical Changes in a Chronic Alcoholic Heart: A Case Study Using 3-Dimensional Electro-Mechanical Heart Modelling
Computing in cardiology, 2024
Laura Bevis, Semhar Biniam Misghina, Elisa Rauseo, Carlos Edgar Lopez Barrera, Gernot Plank, …, Elias Karabelas, Jose Alonso Solis-Lemus, Steven Niederer, …, Caroline H. Roney
Development of a User-Friendly Pipeline for Constructing Atrial Models at Scale: Importance of the End-User for Clinical Uptake
Computing in cardiology, 2024
Manisha Sahota, Fernando Campos, Steven E. Williams, Matthijs Cluitmans, Gernot Plank, Steven Niederer, Martin Bishop
Effect of Scar Interpolation Methods on Simulated Ventricular Tachycardia in Infarcted Heart Models
Computing in cardiology, 2024
Mariya Mamajiwala, Cesare Corrado, Steven Niederer, Richard Wilkinson, Richard H. Clayton
Global Sensitivity Analysis of Left Atrial Electrophysiology Models
Computing in cardiology, 2024
Manisha Sahota, Fernando Campos, Shuang Qian, John Whitaker, Steven E. Williams, Matthijs Cluitmans, Steven Niederer, Martin Bishop
Investigating the Influence of Parameters on Electrogram Morphology Using Gaussian Process Emulators
Computing in cardiology, 2024
Felicity de Vere, Nadeev Wijesuriya, Sandra Howell, Mark K. Elliott, Vishal Mehta, …, Marina Strocchi, Steven A. Niederer, …
Optimizing outcomes from cardiac resynchronization therapy: what do recent data and insights say?
Expert Review of Cardiovascular Therapy, 2024
Shambhavi Malik, Ludovica Cicci, Abdul Qayyum, Rahul Ghelani, Ji-Jian Chow, Alistair Young, Gernot Plank, …, Steven Niederer
Semi Automated Pipeline to Create Anatomical Twins and Perform Electrophysiology Simulations for Hypertrophic Cardiomyopathy
Computing in cardiology, 2024
Fernando Campos, Cristobal Rodero, John Whitaker, Steven Niederer, Gernot Plank, Christopher Aldo Rinaldi, Martin Bishop
Unraveling the Influence of Right Ventricle Presence on Paced ECGs
Computing in cardiology, 2024
Abdul Qayyum, Moona Mazher, Angela Lee, Jose A. Solis-Lemus, Imran Razzak, Steven A. Niederer
Assessment of Left Atrium Motion Deformation Through Full Cardiac Cycle
Lecture notes in computer science, 2024
Yu Deng, Yiyang Xu, Linglong Qian, Anastasia Nasopoulou, Steven Williams, …, Steven Niederer, …
Adaptive Bi-ventricle Surface Reconstruction from Cardiovascular Imaging
Lecture notes in computer science, 2024
O A Jaffery, A Zolotarev, C E Barera, C Rodero, S Niederer, G Slabaugh, W W Good, C H Roney
An in-silico comparison of anatomical and substrate based AF ablation using electro and optical flow mapping
European Heart Journal, 2024
Vitaliy Androshchuk, Natalie Montarello, Nishant Lahoti, Samuel Joseph Hill, Can Zhou, …, Steven Niederer, …
Evolving capabilities of computed tomography imaging for transcatheter valvular heart interventions – new opportunities for precision medicine
The International Journal of Cardiovascular Imaging, 2024
Chris J Oates, Toni Karvonen, Aretha L Teckentrup, Marina Strocchi, Steven A Niederer
Probabilistic Richardson extrapolation
Journal of the Royal Statistical Society Series B (Statistical Methodology), 2024
Nadeev Wijesuriya, Felicity De Vere, Sandra Howell, Nilanka Mannakkara, Paolo Bosco, …, Steven A. Niederer, …
Potential applications of ultrasound-based leadless endocardial pacing in adult congenital heart disease
Heart Rhythm, 2024
Nadeev Wijesuriya, Vishal Mehta, Felicity De Vere, Sandra Howell, Nilanka Mannakkara, …, Steven A. Niederer, …
Left ventricular electrical delay predicts volumetric response to leadless cardiac resynchronization therapy
Heart Rhythm, 2024
Pras Pathmanathan, Kenneth Aycock, Andreu Badal, Ramin Bighamian, Jeff Bodner, …, Steven Niederer
Credibility assessment of in silico clinical trials for medical devices
PLoS Computational Biology, 2024
Nadeev Wijesuriya, Marina Strocchi, Mark Elliott, Vishal Mehta, Felicity De Vere, Sandra Howell, …, Steven A. Niederer, …
Optimizing electrical efficacy of leadless cardiac resynchronization therapy and leadless left ventricular septal pacing: Insights on left and right ventricular activation from electrocardiographic imaging
Heart Rhythm O2, 2024
Johanna Tonko, Angela Lee, N. Mannakkara, Steven E. Williams, Reza Razavi, Martin Bishop, Mark O'Neill, Steven Niederer, …
Structural phenotyping in atrial fibrillation with combined cardiac CT and atrial MRI: Identifying and differentiating individual structural remodelling types in AF
Journal of Cardiovascular Electrophysiology, 2024
Dhani Dharmaprani, Kathryn Tiver, Sobhan Salari Shahrbabaki, Evan V. Jenkins, Darius Chapman, …, Steven A. Niederer, Caroline H. Roney, …
Observable Atrial and Ventricular Fibrillation Episode Durations Are Conformant With a Power Law Based on System Size and Spatial Synchronization
Circulation Arrhythmia and Electrophysiology, 2024
Nadeev Wijesuriya, Vishal Mehta, Felicity De Vere, Sandra Howell, Steven A. Niederer, Haran Burri, …
Heart Size Difference Drives Sex‐Specific Response to Cardiac Resynchronization Therapy: A Post Hoc Analysis of the MORE‐MPP CRT Trial
Journal of the American Heart Association, 2024
Alexandre Lewalle, Gregory Milburn, Kenneth S. Campbell, Steven A. Niederer
Cardiac length-dependent activation driven by force-dependent thick-filament dynamics
Biophysical Journal, 2024
Marica Muffoletto, Hao Xu, Richard Burns, Avan Suinesiaputra, Anastasia Nasopoulou, …, Steven A Niederer, …
Evaluation of deep learning estimation of whole heart anatomy from automated cardiovascular magnetic resonance short- and long-axis analyses in UK Biobank
European Heart Journal - Cardiovascular Imaging, 2024
N Bodagh, K S Tun, A Barton, M Javidi, I Kotadia, …, S Niederer, …
Clinical Turing tests with user certainty analysis to create and validate synthetic electrocardiogram images for artificial intelligence-enhanced algorithm development
EP Europace, 2024
V Vigneswaran, A G Gharaviri, M K Klis, N B Bodagh, I S Sim, C R Roney, …, S N Niederer, …
Enhancing OpenEP: atrial conduction velocity and conduction velocity heterogeneity quantification through EP Workbench
EP Europace, 2024
M Klis, A Gharaviri, V Vigneswaran, I Sim, N Bodagh, S Niederer, …
Heterogenous atrial conduction in patients with hypertrophic cardiomyopathy and atrial fibrillation
EP Europace, 2024
L H G Hopman, J A Solis-Lemus, M B M Hofman, P Bhagirath, S Borodzicz-Jazdzyk, N Van Pouderoijen, A J Krafft, …, S A Niederer, …
Impact of iNAV and dNAV 3D LGE-CMR on the assessment of atrial fibrosis in atrial fibrillation patients
EP Europace, 2024
N Bodagh, I Sim, K S Tun, I Kotadia, M Klis, …, S Niederer, …
Integrating clinical variables with magnetic resonance imaging and electroanatomic mapping parameters to predict response to first-time and repeat atrial fibrillation ablation procedures
EP Europace, 2024
N Wijesuriya, M Strocchi, V S Mehta, M K Elliott, F De Vere, S Howell, …, S A Niederer, …
Optimising electrical performance of leadless cardiac resynchronisation therapy and leadless LV septal pacing
EP Europace, 2024
I Kotadia, R O'dowling, A Aboagye, R Crawley, S Plein, …, S Niederer, …
Predicting atrial fibrillation risk following embolic stroke of unknown source using cardiac magnetic resonance imaging
EP Europace, 2024
K Vickneson, J Tonko, A Gharaviri, M C Williams, M Dweck, …, T Baptiste, J Alonso Solis Lemus, C Corrado, S Niederer, …
Spatial relationship between left peri-atrial fat with underlying arrhythmogenic substrate in patients with atrial fibrillation - innocent bystander or culprit?
EP Europace, 2024
Rodrigo Pommot Berto, Hanna Bugler, Gabriel Dias, Mateus Oliveira, Lucas Ueda, …, Abdul Qayyum, Cristobal Rodero, Steven Niederer, …
Results of the 2023 ISBI challenge to reduce GABA-edited MRS acquisition time
Magnetic Resonance Materials in Physics Biology and Medicine, 2024
Neil Bodagh, Magda Klis, Ali Gharaviri, Vinush Vigneswaran, Keeran Vickneson, …, Steven Niederer, …
Time to capitalise on artificial intelligence in cardiac electrophysiology
Journal of Interventional Cardiac Electrophysiology, 2024
Matteo Salvador, Marina Strocchi, Francesco Regazzoni, Christoph M. Augustin, Luca Dede’, Steven A. Niederer, Alfio Quarteroni
Whole-heart electromechanical simulations using Latent Neural Ordinary Differential Equations
npj Digital Medicine, 2024
Richard J. Gilbertson, Sam Behjati, Anna-Lisa Böttcher, Marianne E. Bronner, Matthew Burridge, …, Steven Niederer, …
The Virtual Child
Cancer Discovery, 2024
Luuk H. G. A. Hopman, José A. Solís-Lemus, Mark B. M. Hofman, Pranav Bhagirath, Sonia Borodzicz-Jazdzyk, Nikki van Pouderoijen, Axel J. Krafft, …, Steven A. Niederer, …
Performance of Image-navigated and Diaphragm-navigated 3D Late Gadolinium-enhanced Cardiac MRI for the Assessment of Atrial Fibrosis
Radiology Cardiothoracic Imaging, 2024
Charles Sillett, Orod Razeghi, Angela W. C. Lee, Jose Alonso Solis Lemus, Caroline Roney, Carlo Mannina, Felicity de Vere, Kiruthika Ananthan, Daniel B. Ennis, …, Steven A. Niederer
A three-dimensional left atrial motion estimation from retrospective gated computed tomography: application in heart failure patients with atrial fibrillation
Frontiers in Cardiovascular Medicine, 2024
Moona Mazher, Abdul Qayyum, M.K.A Ahamed Khan, Steven Niederer, Mastaneh Mokayef, Ridzuan A., Cik Suhana Hassan
Federated Learning on Brain Disease Research: Segmentation of Cerebral Small Vessel Diseases (CSVD) using Multi-scale Hybrid Spatial Deep Learning Approach
Proceedings of International Conference on Artificial Life and Robotics, 2024
Moona Mazher, Abdul Qayyum, M.K.A Ahamed Khan, Steven Niederer, Mastaneh Mokayef, Cik Suhana Hassan, Ridzuan A.
Hybrid Classical and Quantum Deep Learning Models for Medical Image Classification
Proceedings of International Conference on Artificial Life and Robotics, 2024
Abdul Qayyum, Steven Niederer, M.K.A Ahamed Khan, Moona Mazher, Imran Razzak, Mastaneh Mokayef, …
Magnetic Resonance Spectroscopy (MRS) Reconstruction Using Style Transfer Deep Depth wise Framework
Proceedings of International Conference on Artificial Life and Robotics, 2024
Abdul Qayyum, Steven Niederer, M.K.A Ahamed Khan, Moona Mazher, Imran Razzak, Mastaneh Mokayef, …
Parallel Cross Window Attention Transformer and CNN Model for Segmentation of Instrument during Surgery
Proceedings of International Conference on Artificial Life and Robotics, 2024
Marina Strocchi, Steven A. Niederer, Christopher A. Rinaldi
To the Editor—The role of atrioventricular delay in determining right ventricular function with left bundle pacing
Heart Rhythm, 2024
Vishal S. Mehta, YingLiang Ma, Nadeev Wijesuriya, Felicity DeVere, Sandra Howell, …, Hugh O’Brien, Steven Niederer, …
Enhancing transvenous lead extraction risk prediction: Integrating imaging biomarkers into machine learning models
Heart Rhythm, 2024
Moona Mazher, Imran Razzak, Abdul Qayyum, M. Tanveer, Susann Beier, Tariq Khan, Steven A Niederer
Self-supervised spatial–temporal transformer fusion based federated framework for 4D cardiovascular image segmentation
Information Fusion, 2024
Irum D. Kotadia, Robert O'Dowling, Akosua Aboagye, Richard J. Crawley, Neil Bodagh, …, Jose Alonso Solis‐Lemus, Caroline H. Roney, …, Steven Niederer, …
High Prevalence of New Clinically Significant Findings in Patients With Embolic Stroke of Unknown Source Evaluated by Cardiac Magnetic Resonance Imaging
Journal of the American Heart Association, 2024
Abdul Qayyum, Imran Razzak, Moona Mazher, Xuequan Lu, Steven A Niederer
Unsupervised unpaired multiple fusion adaptation aided with self-attention generative adversarial network for scar tissues segmentation framework
Information Fusion, 2024
Fazli Wahid, YingLiang Ma, Vishal Mehta, Sandra Howell, Steven Niederer, C. Aldo Rinaldi
A Deep Learning Framework for Assessing the Risk of Transvenous Lead Extraction Procedures
Lecture notes in computer science, 2024
Marica Muffoletto, Hao Xu, Richard Burns, Avan Suinesiaputra, Anastasia Nasopoulou, …, Steven A. Niederer, …
Evaluation of Deep Learning Estimation of Whole Heart Anatomy FBom Automated Cardiovascular Magnetic Resonance Short- and Long-axis Analyses in UK Biobank
Journal of Cardiovascular Magnetic Resonance, 2024
Marica Muffoletto, Hao Xu, Yiyang Xu, Steven E Williams, Michelle C Williams, …, Steven A Niederer, …
Neural Implicit Functions for 3D Shape Reconstruction from Standard Cardiovascular Magnetic Resonance Views
Lecture notes in computer science, 2024
Caroline H. Roney, Jose Alonso Solis Lemus, Carlos Lopez Barrera, Alexander Zolotarev, Onur Ulgen, Eric Kerfoot, …, Cristobal Rodero, …, Steven Niederer
Constructing bilayer and volumetric atrial models at scale
Interface Focus, 2023
Hamed Keramati, Adelaide de Vecchi, Ronak Rajani, Steven A. Niederer
Using Gaussian process for velocity reconstruction after coronary stenosis applicable in positron emission particle tracking: An in-silico study
PLoS ONE, 2023
Abdul Qayyum, Imran Razzak, Moona Mazher, Tariq Khan, Weiping Ding, Steven Niederer
Two-Stage Self-Supervised Contrastive Learning Aided Transformer for Real-Time Medical Image Segmentation
IEEE Journal of Biomedical and Health Informatics, 2023
Thomas Grandits, Christoph M Augustin, Gundolf Haase, Norbert Jost, Gary R Mirams, Steven A Niederer, …
Neural network emulation of the human ventricular cardiomyocyte action potential for more efficient computations in pharmacological studies
eLife, 2023
Marina Strocchi, Cristobal Rodero, Caroline H. Roney, Caroline Mendonca Costa, Gernot Plank, Pablo Lamata, Steven A. Niederer
A Semi-automatic Pipeline for Generation of Large Cohorts of Four-Chamber Heart Meshes
Methods in molecular biology, 2023
Abdul Qayyum, Moona Mazher, Imran Razzak, Steven Niederer
Multiscale Kernel Atrous Convolution Network for Segmentation of Myocardium
International Conference on Digital Image Computing: Techniques and Applications (DICTA), 2023
Semhar Misghina, Jose Alonso Solis-Lemus, Edward Vigmond, steven niederer, Caroline Roney
Biatrial Modelling for in Silico Prediction of Atrial Fibrillation Inducibility
Computing in cardiology, 2023
Cristobal Rodero, Tiffany M. G. Baptiste, Rosie K. Barrows, Alexandre Lewalle, Steven A. Niederer, Marina Strocchi
Advancing clinical translation of cardiac biomechanics models: a comprehensive review, applications and future pathways
Frontiers in Physics, 2023
Marina Strocchi, Nadeev Wijesuriya, Vishal Mehta, Felicity de Vere, Christopher A. Rinaldi, Steven A. Niederer
Computational Modelling Enabling In Silico Trials for Cardiac Physiologic Pacing
Journal of Cardiovascular Translational Research, 2023
Jérôme Lamy, Roy Taoutel, Romy Chamoun, Joseph Akar, Steven Niederer, Hamid Mojibian, …
Atrial fibrosis by cardiac MRI is a correlate for atrial stiffness in patients with atrial fibrillation
The International Journal of Cardiovascular Imaging, 2023
Irum D. Kotadia, Maria Dias, Caroline Roney, Richard A. Parker, Robert O’Dowling, Neil Bodagh, …, Steven Niederer, …
AF and in-hospital mortality in COVID-19 patients
Heart Rhythm O2, 2023
Nadeev Wijesuriya, Vishal Mehta, Felicity De Vere, Sandra Howell, Jonathan M. Behar, …, Steven A. Niederer, …
Cost‐effectiveness analysis of leadless cardiac resynchronization therapy
Journal of Cardiovascular Electrophysiology, 2023
Felicity de Vere, Nadeev Wijesuriya, Mark K. Elliott, Vishal Mehta, Sandra Howell, Martin Bishop, Marina Strocchi, Steven A. Niederer, …
Managing arrhythmia in cardiac resynchronisation therapy
Frontiers in Cardiovascular Medicine, 2023
Matthew O’Connor, Umberto Barbero, Daniel B Kramer, Angela Lee, Alina Hua, Tevfik Ismail, …, Steven Niederer, …
Anatomic, histologic, and mechanical features of the right atrium: implications for leadless atrial pacemaker implantation
EP Europace, 2023
Mark K. Elliott, Marina Strocchi, Benjamin J. Sieniewicz, Vishal Mehta, Nadeev Wijesuriya, Felicity deVere, …, Martin J. Bishop, Steven Niederer, …
Left bundle branch area pacing reduces epicardial dispersion of repolarization compared with biventricular cardiac resynchronization therapy
Heart Rhythm, 2023
Vishal S Mehta, Nadeev Wijesuriya, Felicity DeVere, Sandra Howell, Mark K Elliott, …, Steven Niederer, …
Long-term survival following transvenous lead extraction: unpicking differences according to sex
EP Europace, 2023
Baldeep S. Sidhu, Angela W.C. Lee, Justin Gould, Bradley Porter, Benjamin Sieniewicz, Mark K. Elliott, …, Steven A. Niederer
Guided implantation of a leadless left ventricular endocardial electrode and acoustic transmitter using computed tomography anatomy, dynamic perfusion and mechanics, and predicted activation pattern
Heart Rhythm, 2023
Marina Strocchi, Stefano Longobardi, Christoph M. Augustin, Matthias A. F. Gsell, Argyrios Petras, Christopher A. Rinaldi, …, Steven A. Niederer
Cell to whole organ global sensitivity analysis on a four-chamber heart electromechanics model using Gaussian processes emulators
PLoS Computational Biology, 2023
Cristobal Rodero, Tiffany M G Baptiste, Rosie K Barrows, Hamed Keramati, Charles P Sillett, Marina Strocchi, Pablo Lamata, Steven A Niederer
A systematic review of cardiac in-silico clinical trials
Progress in Biomedical Engineering, 2023
Nadeev Wijesuriya, Vishal Mehta, Felicity De Vere, Marina Strocchi, Jonathan M. Behar, Steven A. Niederer, Christopher A. Rinaldi
The role of conduction system pacing in patients with atrial fibrillation
Frontiers in Cardiovascular Medicine, 2023
I Kotadia, M Dias, C Roney, R A Parker, R O'dowling, D O'hare, J A Solis-Lemus, …, S Niederer, …
Atrial fibrillation and in-hospital mortality in Covid-19 patients
EP Europace, 2023
S Qian, D Ugurlu, E Fairweather, M Strocchi, L Dal Toso, Y Deng, A Young, M Bishop, …, S Niederer
Cardiac digital twins of the adult population: linking electrophysiological functions to anatomy
EP Europace, 2023
N Bodagh, O Ali, I Kotadia, I Sim, A Gharaviri, …, J Solis-Lemus, T Baptiste, C Corrado, S Niederer, …
Feasibility of artificial intelligence-enhanced electrocardiogram (AI-ECG) analysis in the current clinical environment: An online survey
EP Europace, 2023
C Roney, J S L Alonso, I Sim, O Ulgen, C Rodero, M Strocchi, I Kotadia, …, S Niederer
In silico biatrial fibrosis ablation improves atrial fibrillation outcome
EP Europace, 2023
S Williams, D Buytaert, N Bodagh, I Kotadia, A Gharaviri, T Baptiste, C Corrado, J Solis-Lemus, S Niederer, …
Mitral annular electrogram morphology - a balanced signal does not identify the anatomical annulus
EP Europace, 2023
A Gharaviri, N Bodagh, I Kotaida, T Baptiste, C Corrado, I Sim, J A S Lemus, S Niederer, J Whitaker, …
Performance of atrial conduction velocity algorithms: a comparative in-silico study
EP Europace, 2023
K Vickneson, J Tonko, M C Williams, A Gharaviri, M Dweck, T Baptiste, J Alonso Solis Lemus, C Corrado, S Niederer, …
Volumetric quantification of peri-atrial fat inflammation in atrial fibrillation patients
EP Europace, 2023
José Alonso Solís-Lemus, Tiffany Baptiste, Rosie Barrows, Charles Sillett, Ali Gharaviri, Giulia Raffaele, Orod Razeghi, Marina Strocchi, Iain Sim, Irum Kotadia, …, Caroline Roney, Steven Niederer
Evaluation of an open-source pipeline to create patient-specific left atrial models: A reproducibility study
Computers in Biology and Medicine, 2023
Neil Bodagh, Irum Kotadia, Ali Gharaviri, Fernando Zelaya, Jonathan Birns, …, Steven Niederer, …
The Impact of Atrial Fibrillation Treatment Strategies on Cognitive Function
Journal of Clinical Medicine, 2023
Nadeev Wijesuriya, Felicity De Vere, Vishal Mehta, Steven Niederer, Christopher A Rinaldi, Jonathan M Behar
Leadless Pacing: Therapy, Challenges and Novelties
Arrhythmia & Electrophysiology Review, 2023
Luuk H G A Hopman, Irene M Frenaij, José A Solís-Lemus, Sulayman el Mathari, Steven A Niederer, Cornelis P Allaart, Marco J W Götte
Quantification of left atrial appendage fibrosis by cardiac magnetic resonance: an accurate surrogate for left atrial fibrosis in atrial fibrillation patients?
EP Europace, 2023
Neil Bodagh, Michelle C. Williams, Keeran Vickneson, Ali Gharaviri, Steven Niederer, Steven E. Williams
State of the art paper: Cardiac computed tomography of the left atrium in atrial fibrillation
Journal of cardiovascular computed tomography, 2023
Orod Razeghi, Ridhima Kapoor, Mahmood I. Alhusseini, Muhammad Fazal, Siyi Tang, Caroline H. Roney, …, Steven Niederer, …
Atrial fibrillation ablation outcome prediction with a machine learning fusion framework incorporating cardiac computed tomography
Journal of Cardiovascular Electrophysiology, 2023
Argyrios Petras, Matthias A.F. Gsell, Christoph M. Augustin, Jairo Rodriguez-Padilla, Alexander Jung, Marina Strocchi, …, Steven A. Niederer, …
Mechanoelectric effects in healthy cardiac function and under Left Bundle Branch Block pathology
Computers in Biology and Medicine, 2023
Marina Strocchi, Karli Gillette, Aurel Neic, Mark K. Elliott, Nadeev Wijesuriya, …, Steven A. Niederer
Effect of scar and His–Purkinje and myocardium conduction on response to conduction system pacing
Journal of Cardiovascular Electrophysiology, 2023
Hao Xu, Steven E Williams, Michelle C Williams, David E Newby, Jonathan Taylor, …, Steven A Niederer, …
Deep learning estimation of three-dimensional left atrial shape from two-chamber and four-chamber cardiac long axis views
European Heart Journal - Cardiovascular Imaging, 2023
Alexandre Lewalle, Gregory Milburn, Kenneth S. Campbell, Steven A. Niederer
Modeling mechanisms of the thick-filament off-state dynamics in cardiac muscle
Biophysical Journal, 2023
Nadeev Wijesuriya, Mark K. Elliott, Vishal Mehta, Felicity De Vere, Marina Strocchi, Jonathan M. Behar, Steven A. Niederer, …
Pacing interventions in non-responders to cardiac resynchronization therapy
Frontiers in Physiology, 2023
Damiano Fassina, Caroline M. Costa, Martin Bishop, Gernot Plank, John Whitaker, Sian E. Harding, Steven A. Niederer
Assessing the arrhythmogenic risk of engineered heart tissue patches through in silico application on infarcted ventricle models
Computers in Biology and Medicine, 2023
Cesare Corrado, Caroline H. Roney, Orod Razeghi, Josè Alonso Solís Lemus, Sam Coveney, Iain Sim, Steven E. Williams, Mark D. O’Neill, …, Steven A. Niederer
Quantifying the impact of shape uncertainty on predicted arrhythmias
Computers in Biology and Medicine, 2023
YingLiang Ma, Vishal S. Mehta, C. Aldo Rinaldi, Pengpeng Hu, Steven Niederer, Reza Razavi
Automatic Detection of Coil Position in the Chest X-ray Images for Assessing the Risks of Lead Extraction Procedures
Lecture notes in computer science, 2023
Angela W. C. Lee, Marina Strocchi, Cristobal Rodero, Caroline Mendonca Costa, Steven A. Niederer
Computational Biomechanics of Ventricular Dyssynchrony and Resynchronization Therapy
Cardiac and vascular biology, 2023
Justina Ghebryal, Cristobal Rodero, Rosie K. Barrows, Marina Strocchi, Caroline H. Roney, Christoph M. Augustin, Gernot Plank, Steven A. Niederer
Effect of Varying Pericardial Boundary Conditions on Whole Heart Function: A Computational Study
Lecture notes in computer science, 2023
Yu Deng, Hao Xu, Sashya Rodrigo, Steven E. Williams, Michelle C. Williams, Steven A. Niederer, …
ModusGraph: Automated 3D and 4D Mesh Model Reconstruction from Cine CMR with Improved Accuracy and Efficiency
Lecture notes in computer science, 2023
Abdul Qayyum, Moona Mazher, Steven Niederer, Imran Razzak
Segmentation of Intra-operative Ultrasound Using Self-supervised Learning Based 3D-ResUnet Model with Deep Supervision
Lecture notes in computer science, 2023
Hao Xu, Marica Muffoletto, Steven A. Niederer, Steven E. Williams, Michelle C. Williams, Alistair A. Young
Whole Heart 3D Shape Reconstruction from Sparse Views: Leveraging Cardiac Computed Tomography for Cardiovascular Magnetic Resonance
Lecture notes in computer science, 2023
Samuel Coveney, Cesare Corrado, Caroline Roney, Richard D. Wilkinson, Jeremy Oakley, steven niederer, Richard H. Clayton
A Workflow for Probabilistic Calibration of Models of Left Atrial Electrophysiology
Computing in cardiology, 2022
Rosie Kate Barrows, Marina Strocchi, Christoph M. Augustin, Matthias A. F. Gsell, Caroline H. Roney, Jose A. Solis-Lemus, Hao Xu, Karli K. Gillette, …, Martin J. Bishop, …, Steven A. Niederer
The Effect of Heart Rate and Atrial Contraction on Left Ventricular Function
Computing in cardiology, 2022
Tiffany MG Baptiste, Angela Lee, Marina Strocchi, Charles Sillett, Daniel B. Ennis, Ulrike Haberland, Ronak Rajani, Aldo Rinaldi, Steven A. Niederer
The Influence of Left Atrial Wall Thickness and Curvature on Wall Strain in Patient-Specific Atrium Models
Computing in cardiology, 2022
Steven E. Williams, Paul Smith, Ali Gharaviri, Chris O'Shea, Adam Connolly, …, Steven Niederer, …
Updates on OpenEP: The Open-Source Platform for Elec-trophysiological Data Analysis
Computing in cardiology, 2022
Marina Strocchi, Nadeev Wijesuriya, Mark K. Elliott, Karli Gillette, Aurel Neic, …, Steven A. Niederer
Leadless biventricular left bundle and endocardial lateral wall pacing versus left bundle only pacing in left bundle branch block patients
Frontiers in Physiology, 2022
Marina Riabiz, Jon Cockayne, Antao Luo, Chris Oates, Pawel Swietach, Steven Niederer
Novel developments in inferring variability and co-variability of calcium signalling
Journal of Molecular and Cellular Cardiology, 2022
Jiyue He, Arkady M. Pertsov, Elizabeth M. Cherry, Flavio H. Fenton, Caroline H. Roney, Steven A. Niederer, Zirui Zang, …
Fiber Organization Has Little Effect on Electrical Activation Patterns During Focal Arrhythmias in the Left Atrium
IEEE Transactions on Biomedical Engineering, 2022
Marcha Verheijen, Ugis Sarkans, Witold Wolski, Danyel Jennen, Florian Caiment, …, Alex Lewalle, …, Steven Niederer, …
Multi-omics HeCaToS dataset of repeated dose toxicity for cardiotoxic & hepatotoxic compounds
Scientific Data, 2022
Mark K. Elliott, Marina Strocchi, Benjamin J. Sieniewicz, Baldeep Sidhu, Vishal Mehta, Nadeev Wijesuriya, …, Steven Niederer, …
Biventricular endocardial pacing and left bundle branch area pacing for cardiac resynchronization: Mechanistic insights from electrocardiographic imaging, acute hemodynamic response, and magnetic resonance imaging
Heart Rhythm, 2022
Cristobal Rodero, Stefano Longobardi, Christoph Augustin, Marina Strocchi, Gernot Plank, Pablo Lamata, Steven A. Niederer
Calibration of Cohorts of Virtual Patient Heart Models Using Bayesian History Matching
Annals of Biomedical Engineering, 2022
Hugh O’Brien, John Whitaker, Mark D. O’Neill, Karine Grigoryan, Harminder Gill, …, Steven Niederer
Regional left ventricle scar detection from routine cardiac computed tomography angiograms using latent space classification
Computers in Biology and Medicine, 2022
Suran Galappaththige, Richard A. Gray, Caroline Mendonca Costa, Steven Niederer, Pras Pathmanathan
Credibility assessment of patient-specific computational modeling using patient-specific cardiac modeling as an exemplar
PLoS Computational Biology, 2022
Sam Coveney, Caroline H. Roney, Cesare Corrado, Richard D. Wilkinson, Jeremy E. Oakley, Steven A. Niederer, Richard H. Clayton
Calibrating cardiac electrophysiology models using latent Gaussian processes on atrial manifolds
Scientific Reports, 2022
Marina Strocchi, Karli Gillette, Aurel Neic, Mark K. Elliott, Nadeev Wijesuriya, …, Steven A. Niederer
Comparison between conduction system pacing and cardiac resynchronization therapy in right bundle branch block patients
Frontiers in Physiology, 2022
John Whitaker, Paul C. Zei, Shahreen Ahmad, Steven Niederer, Mark O'Neill, Christopher A. Rinaldi
The effect of ionizing radiation through cardiac stereotactic body radiation therapy on myocardial tissue for refractory ventricular arrhythmias: A review
Frontiers in Cardiovascular Medicine, 2022
Mark K. Elliott, Felicity de Vere, Vishal S. Mehta, Nadeev Wijesuriya, Marina Strocchi, Ronak Rajani, Steven Niederer, …
Rate or Rhythm Control in CRT (RHYTHMIC): Study rationale and protocol
Heart Rhythm O2, 2022
Evan V. Jenkins, Dhani Dharmaprani, Madeline Schopp, Jing Xian Quah, Kathryn Tiver, …, Caroline H. Roney, Steven A. Niederer, …
The inspection paradox: An important consideration in the evaluation of rotor lifetimes in cardiac fibrillation
Frontiers in Physiology, 2022
Nadeev Wijesuriya, Mark K Elliott, Vishal Mehta, Jonathan M Behar, Steven Niederer, Bruce L Wilkoff, …
Transvenous lead extraction in conduction system pacing
Frontiers in Physiology, 2022
Mark K. Elliott, Pasquale Vergara, Nadeev Wijesuriya, Vishal S. Mehta, Paolo Bosco, …, Steven Niederer, …
Feasibility of leadless left ventricular septal pacing with the WiSE-CRT system to target the left bundle branch area: A porcine model and multicenter patient experience
Heart Rhythm, 2022
Luuk H G A Hopman, Julia E Visch, Pranav Bhagirath, Anja M van der Laan, Mark J Mulder, Orod Razeghi, Michiel J B Kemme, Steven A Niederer, …
Right atrial function and fibrosis in relation to successful atrial fibrillation ablation
European Heart Journal - Cardiovascular Imaging, 2022
Vishal S. Mehta, Salma Ayis, Mark K. Elliott, Nadeev Widjesuriya, Nuha Kardaman, …, Steven Niederer, …
The role of guidance in delivering cardiac resynchronization therapy: A systematic review and network meta-analysis
Heart Rhythm O2, 2022
Louisa O’Neill, Iain Sim, Daniel O’Hare, John Whitaker, Rahul K. Mukherjee, Steven Niederer, …
Provocation and localization of atrial ectopy in patients with atrial septal defects
Journal of Interventional Cardiac Electrophysiology, 2022
Stefano Longobardi, Anna Sher, Steven A. Niederer
Quantitative mapping of force–pCa curves to whole‐heart contraction and relaxation
The Journal of Physiology, 2022
Nadeev Wijesuriya, Mark K. Elliott, Vishal Mehta, Baldeep S. Sidhu, Marina Strocchi, Jonathan M. Behar, Steven Niederer, …
Leadless Left Bundle Branch Area Pacing in Cardiac Resynchronisation Therapy: Advances, Challenges and Future Directions
Frontiers in Physiology, 2022
Fernando O. Campos, Aurel Neic, Caroline Mendonca Costa, John Whitaker, Mark O’Neill, Reza Razavi, …, Steven A. Niederer, …, Martin J. Bishop
An automated near-real time computational method for induction and treatment of scar-related ventricular tachycardias
Medical Image Analysis, 2022
I Sim, O Razeghi, JA Solis Lemus, R Mukherjee, D O’hare, L O’neill, I Kotadia, CH Roney, …, S Niederer, …
Atrial tissue characterisation using electroanatomic voltage mapping and cardiac magnetic resonance imaging
EP Europace, 2022
MK Elliott, M Strocchi, VS Mehta, N Wijesuriya, NN Mannakkara, JM Behar, MJ Bishop, S Niederer, …
Dispersion of repolarization increases after cardiac resynchronization therapy in patients who do not undergo left ventricular reverse remodelling
EP Europace, 2022
I Sim, L O’neill, J Whitaker, R Mukherjee, D O’hare, …, S Niederer, …
Dynamic voltage attenuation identifies atrial fibrosis in a rabbit model: simultaneous assessment with optical mapping and contact electrogram mapping
EP Europace, 2022
S Williams, CH Roney, A Connolly, P Smith, M Bishop, S Niederer, J Whitaker, C Corrado, I Kotadia, …
Interpolation of electrophysiology parameters using OpenEP: technology development and clinical application
EP Europace, 2022
P Smith, M Bishop, J Rajan, E Kerfoot, I Sim, I Kotadia, …, C Corrado, …, C Roney, S Niederer, …
OpenEP-Py and OpenEP-GUI: An interactive platform for the visualisation and analysis of clinical and simulated cardiac electrophysiology data
EP Europace, 2022
F Campos, AN Neic, CMC Mendonca Costa, JW Whitaker, MON O’neill, RR Razavi, …, SAN Niederer, …, MJB Bishop
Virtual induction and treatment of arrhythmias (VITA): a fast automated computational tool to induce scar-related tachycardia and identify ablation targets
EP Europace, 2022
Hugh O'Brien, Michelle C. Williams, Ronak Rajani, Steven Niederer
Radiomics and Machine Learning for Detecting Scar Tissue on CT Delayed Enhancement Imaging
Frontiers in Cardiovascular Medicine, 2022
Vishal S. Mehta, Hugh O’Brien, Mark K. Elliott, Nadeev Wijesuriya, Angelo Auricchio, Salma Ayis, …, Steven Niederer, …
Machine learning–derived major adverse event prediction of patients undergoing transvenous lead extraction: Using the ESC EHRA EORP European lead extraction ConTRolled ELECTRa registry
Heart Rhythm, 2022
Mark K. Elliott, Marina Strocchi, Vishal S. Mehta, Nadeev Wijesuriya, Nilanka N. Mannakkara, Tom Jackson, …, Martin J. Bishop, Steven Niederer, …
Dispersion of repolarization increases with cardiac resynchronization therapy and is associated with left ventricular reverse remodeling
Journal of Electrocardiology, 2022
Marina Riabiz, Wilson Ye Chen, Jon Cockayne, Pawel Swietach, Steven A. Niederer, Lester Mackey, …
Optimal Thinning of MCMC Output
Journal of the Royal Statistical Society Series B (Statistical Methodology), 2022
Damiano Fassina, Caroline M. Costa, Stefano Longobardi, Elias Karabelas, Gernot Plank, Sian E. Harding, Steven A. Niederer
Modelling the interaction between stem cells derived cardiomyocytes patches and host myocardium to aid non-arrhythmic engineered heart tissue design
PLoS Computational Biology, 2022
Elias Karabelas, Stefano Longobardi, Jana Fuchsberger, Orod Razeghi, Cristobal Rodero, Marina Strocchi, Ronak Rajani, Gundolf Haase, Gernot Plank, Steven Niederer
Global Sensitivity Analysis of Four Chamber Heart Hemodynamics Using Surrogate Models
IEEE Transactions on Biomedical Engineering, 2022
Cristobal Rodero, Pablo Lamata, Steven Alexander Niederer
Cardiac Simulations: Computer Games to Mend Broken Hearts
Frontiers for Young Minds, 2022
Yingjing Feng, Caroline H. Roney, Jason D. Bayer, Steven A. Niederer, Mélèze Hocini, Edward J. Vigmond
Detection of focal source and arrhythmogenic substrate from body surface potentials to guide atrial fibrillation ablation
PLoS Computational Biology, 2022
Mark K Elliott, Vishal Mehta, Nadeev Wijesuriya, Baldeep S Sidhu, Justin Gould, Steven Niederer, …
Multi-lead pacing for cardiac resynchronization therapy in heart failure: a meta-analysis of randomized controlled trials
European Heart Journal Open, 2022
Nadeev Wijesuriya, Mark K. Elliott, Vishal Mehta, Baldeep S. Sidhu, Jonathan M. Behar, Steven Niederer, …
Leadless left ventricular endocardial pacing for cardiac resynchronization therapy: A systematic review and meta-analysis
Heart Rhythm, 2022
Vishal S Mehta, Mark K Elliott, Nadeev Wijesuriya, Steven Niederer, Christopher A Rinaldi
Reply to Usefulness of Multisite Ventricular Pacing in Nonresponders to Cardiac Resynchronization Therapy
The American Journal of Cardiology, 2022
Anna Sher, Steven A. Niederer, Gary R. Mirams, Anna Kirpichnikova, Richard Allen, Pras Pathmanathan, …
A Quantitative Systems Pharmacology Perspective on the Importance of Parameter Identifiability
Bulletin of Mathematical Biology, 2022
Sian O' Brien, Andrew P. Holmes, Daniel M. Johnson, S. Nashitha Kabir, Christopher O' Shea, …, Adelisa Avezzu, …, Steven Niederer, …
Increased atrial effectiveness of flecainide conferred by altered biophysical properties of sodium channels
Journal of Molecular and Cellular Cardiology, 2022
Caroline H. Roney, Iain Sim, Jin Yu, Marianne Beach, Arihant Mehta, Jose Alonso Solis-Lemus, …, Cesare Corrado, Orod Razeghi, …, Steven A. Niederer
Predicting Atrial Fibrillation Recurrence by Combining Population Data and Virtual Cohorts of Patient-Specific Left Atrial Models
Circulation Arrhythmia and Electrophysiology, 2022
Mark K. Elliott, Caroline Mendonca Costa, John Whitaker, Philip Gemmell, Vishal S. Mehta, Baldeep S. Sidhu, Justin Gould, …, Steven Niederer, Martin J. Bishop, …
Effect of scar and pacing location on repolarization in a porcine myocardial infarction model
Heart Rhythm O2, 2022
Irum D. Kotadia, Robert O’Dowling, Akosua Aboagye, Iain Sim, Daniel O’Hare, …, Caroline H. Roney, …, Steven Niederer, …
Atrial CARdiac Magnetic resonance imaging in patients with embolic stroke of unknown source without documented Atrial Fibrillation (CARM-AF): Study design and clinical protocol
Heart Rhythm O2, 2022
Abdul Qayyum, Moona Mazher, Steven Niederer, Fabrice Meriaudeau, Imran Razzak
Automatic Cardiac Magnetic Resonance Respiratory Motions Assessment and Segmentation
Lecture notes in computer science, 2022
Alex Lewalle, Kenneth S. Campbell, Stuart G. Campbell, Gregory N. Milburn, Steven A. Niederer
Functional and structural differences between skinned and intact muscle preparations
The Journal of General Physiology, 2021
Stefano Longobardi, Anna Sher, Steven A. Niederer
In silico identification of potential calcium dynamics and sarcomere targets for recovering left ventricular function in rat heart failure with preserved ejection fraction
PLoS Computational Biology, 2021
Mark K. Elliott, Vishal S. Mehta, Dejana Martic, Baldeep S. Sidhu, Steven Niederer, Christopher A. Rinaldi
Atrial fibrillation in cardiac resynchronization therapy
Heart Rhythm O2, 2021
Jana Fuchsberger, Philipp Aigner, Steven Niederer, Gernot Plank, Heinrich Schima, Gundolf Haase, Elias Karabelas
On the incorporation of obstacles in a fluid flow problem using a Navier–Stokes–Brinkman penalization approach
Journal of Computational Science, 2021
Cristobal Rodero, Marina Strocchi, Angela W.C. Lee, Christopher A. Rinaldi, Edward J. Vigmond, Gernot Plank, Pablo Lamata, Steven A. Niederer
Impact of anatomical reverse remodelling in the design of optimal quadripolar pacing leads: A computational study
Computers in Biology and Medicine, 2021
Vishal S. Mehta, Hugh O’Brien, Mark K. Elliott, Baldeep S. Sidhu, Justin Gould, Anoop K. Shetty, Steven Niederer, …
Assessing long-term survival and hospitalization following transvenous lead extraction in patients with cardiac resynchronization therapy devices: A propensity score–matched analysis
Heart Rhythm O2, 2021
Vishal S. Mehta, Mark K. Elliott, Baldeep S. Sidhu, Justin Gould, Bradley Porter, Steven Niederer, …
“Is multipoint pacing superior to optimized single‐point pacing?”—Authors' reply
Journal of Cardiovascular Electrophysiology, 2021
John Whitaker, Radhouene Neji, Steven Kim, Adam Connolly, Thierry Aubriot, …, Caroline H. Roney, …, Steven Niederer, …, Martin J. Bishop, …
Late Gadolinium Enhancement Cardiovascular Magnetic Resonance Assessment of Substrate for Ventricular Tachycardia With Hemodynamic Compromise
Frontiers in Cardiovascular Medicine, 2021
Mark K. Elliott, Vishal S. Mehta, Baldeep Singh Sidhu, Steven Niederer, Christopher A. Rinaldi
Endocardial left ventricular pacing
Herz, 2021
Justin Gould, Simon Claridge, Thomas Jackson, Benjamin J Sieniewicz, Baldeep S Sidhu, …, Steven Niederer, …
Standard care vs. TRIVEntricular pacing in Heart Failure (STRIVE HF): a prospective multicentre randomized controlled trial of triventricular pacing vs. conventional biventricular pacing in patients with heart failure and intermediate QRS left bundle branch block
EP Europace, 2021
Caroline H Roney, Charles Sillett, John Whitaker, Jose Alonso Solis Lemus, Iain Sim, Irum Kotadia, Mark O'Neill, …, Steven A Niederer
Applications of multimodality imaging for left atrial catheter ablation
European Heart Journal - Cardiovascular Imaging, 2021
Caroline H. Roney, Nicholas Child, Bradley Porter, Iain Sim, John Whitaker, …, Steven A. Niederer
Time-Averaged Wavefront Analysis Demonstrates Preferential Pathways of Atrial Fibrillation, Predicting Pulmonary Vein Isolation Acute Response
Frontiers in Physiology, 2021
Mark K Elliott, Peggy Jacon, Baldeep Singh Sidhu, Lucy Jarrett Smith, Vishal S Mehta, …, Angela W C Lee, Steven Niederer, …
Technical feasibility of leadless left bundle branch area pacing for cardiac resynchronization: a case series
European Heart Journal - Case Reports, 2021
Louisa O’Neill, Iain Sim, Daniel O’Hare, John Whitaker, Rahul K Mukherjee, Orod Razeghi, Steven Niederer, …
CArdiac MagnEtic resonance assessment of bi-Atrial fibrosis in secundum atrial septal defects patients: CAMERA-ASD study
European Heart Journal - Cardiovascular Imaging, 2021
Angela W.C. Lee, Orod Razeghi, Jose Alonso Solis-Lemus, Marina Strocchi, Baldeep Sidhu, Justin Gould, Jonathan M. Behar, Mark Elliott, …, Steven A. Niederer
Non-invasive simulated electrical and measured mechanical indices predict response to cardiac resynchronization therapy
Computers in Biology and Medicine, 2021
Vishal S Mehta, Mark K Elliott, Baldeep S Sidhu, Justin Gould, Bradley Porter, Steven Niederer, …
Multipoint pacing for cardiac resynchronisation therapy in patients with heart failure: A systematic review and meta‐analysis
Journal of Cardiovascular Electrophysiology, 2021
Mark K. Elliott, Joshua Blauer, Vishal S. Mehta, Baldeep S. Sidhu, Justin Gould, …, Steven Niederer, …
Comparison of electrical dyssynchrony parameters between electrocardiographic imaging and a simulated ECG belt
Journal of Electrocardiology, 2021
Sam Coveney, Cesare Corrado, Jeremy E. Oakley, Richard D. Wilkinson, Steven A. Niederer, Richard H. Clayton
Bayesian Calibration of Electrophysiology Models Using Restitution Curve Emulators
Frontiers in Physiology, 2021
Hugh O'Brien, John Whitaker, Baldeep Singh Sidhu, Justin Gould, Tanja Kurzendorfer, …, Steven Niederer
Automated Left Ventricle Ischemic Scar Detection in CT Using Deep Neural Networks
Frontiers in Cardiovascular Medicine, 2021
Baldeep S. Sidhu, Justin Gould, Mark K. Elliott, Vishal S. Mehta, Steven A. Niederer, Gerald Carr-White, …
Clinical effectiveness of a dedicated cardiac resynchronization therapy pre-assessment clinic incorporating cardiac magnetic resonance imaging and cardiopulmonary exercise testing on patient selection and outcomes
IJC Heart & Vasculature, 2021
Baldeep Singh Sidhu, Benjamin Sieniewicz, Justin Gould, Mark K Elliott, Vishal S Mehta, …, Steven A Niederer, …
Leadless left ventricular endocardial pacing for CRT upgrades in previously failed and high-risk patients in comparison with coronary sinus CRT upgrades
EP Europace, 2021
Baldeep S. Sidhu, Simon Claridge, Haotian Gu, Ye Li, Justin Gould, …, Steven A. Niederer, …
The physiological effects of cardiac resynchronization therapy on aortic and pulmonary flow and dynamic and static components of systemic impedance
Heart Rhythm O2, 2021
MK Elliott, M Strocchi, BS Sidhu, V Mehta, B Porter, J Gould, S Niederer, …
Acute hemodynamic response of epicardial and endocardial cardiac resynchronization therapy, His bundle pacing and left bundle branch pacing
EP Europace, 2021
VS Mehta, MK Elliott, BS Sidhu, H O’brien, J Gould, R Razavi, S Niederer, …
Assessing survival and re-hospitalisation following transvenous lead extraction in cardiac resynchronisation therapy devices depending on reimplantation timing: a propensity score matched analysis
EP Europace, 2021
VS Mehta, MK Elliott, BS Sidhu, J Gould, V Vergani, …, S Niederer, …
Long-term survival following transvenous lead extraction: importance of indication and comorbidities
EP Europace, 2021
VS Mehta, H O’brien, MK Elliott, BS Sidhu, J Gould, R Razavi, S Niederer, …
Machine learning based major complication prediction for patients undergoing transvenous lead extraction
EP Europace, 2021
Savannah F. Bifulco, Griffin D. Scott, Sakher Sarairah, Zeinab Birjandian, Caroline H. Roney, Steven A. Niederer, Christian Mahnkopf, …
Computational modeling identifies embolic stroke of undetermined source patients with potential arrhythmic substrate
eLife, 2021
Cristobal Rodero, Marina Strocchi, Maciej Marciniak, Stefano Longobardi, John Whitaker, Mark D. O’Neill, Karli Gillette, …, Steven A. Niederer
Linking statistical shape models and simulated function in the healthy adult human heart
PLoS Computational Biology, 2021
Baldeep S Sidhu, Justin Gould, Mark K Elliott, Vishal Mehta, Steven Niederer, Christopher A Rinaldi
Leadless Left Ventricular Endocardial Pacing and Left Bundle Branch Area Pacing for Cardiac Resynchronisation Therapy
Arrhythmia & Electrophysiology Review, 2021
Orod Razeghi, Mattias Heinrich, Thomas E. Fastl, Cesare Corrado, Rashed Karim, Adelaide De Vecchi, …, Steven Niederer
Hyperparameter optimisation and validation of registration algorithms for measuring regional ventricular deformation using retrospective gated computed tomography images
Scientific Reports, 2021
Steven E. Williams, Caroline H. Roney, Adam Connolly, Iain Sim, John Whitaker, Daniel O’Hare, …, Cesare Corrado, Martin Bishop, Steven A. Niederer, …
OpenEP: A Cross-Platform Electroanatomic Mapping Data Format and Analysis Platform for Electrophysiology Research
Frontiers in Physiology, 2021
Justin Gould, Baldeep S. Sidhu, Benjamin J. Sieniewicz, Bradley Porter, Angela W. C. Lee, Orod Razeghi, Jonathan M. Behar, …, Steven Niederer, …
Feasibility of intraprocedural integration of cardiac CT to guide left ventricular lead implantation for CRT upgrades
Journal of Cardiovascular Electrophysiology, 2021
Manav Sohal, Shoaib Hamid, Giovanni Perego, Paolo Della Bella, Shaumik Adhya, …, Steven Niederer, …
A multicenter prospective randomized controlled trial of cardiac resynchronization therapy guided by invasive dP/dt
Heart Rhythm O2, 2021
Thomas Jackson, Simon Claridge, Jonathan Behar, Cheng Yao, Mark Elliott, …, Steven Niederer, …
Noninvasive electrocardiographic assessment of ventricular activation and remodeling response to cardiac resynchronization therapy
Heart Rhythm O2, 2021
Orod Razeghi, Marina Strocchi, Cesare Corrado, Henry Chubb, Ronak Rajani, Daniel B. Ennis, Steven A. Niederer
Impact of Image Resolution and Resampling on Motion Tracking of the Left Chambers from Cardiac Scans
Lecture notes in computer science, 2021
Stefano Longobardi, Anna Sher, Steven A. Niederer
In Silico Mapping of the Omecamtiv Mecarbil Effects from the Sarcomere to the Whole-Heart and Back Again
Lecture notes in computer science, 2021
Charles Sillett, Orod Razeghi, Marina Strocchi, Caroline H. Roney, Hugh O’Brien, Daniel B. Ennis, Ulrike Haberland, Ronak Rajani, Christopher A. Rinaldi, Steven A. Niederer
Optimisation of Left Atrial Feature Tracking Using Retrospective Gated Computed Tomography Images
Lecture notes in computer science, 2021
Marina Strocchi, Christoph M. Augustin, Matthias A. F. Gsell, Elias Karabelas, Aurel Neic, Karli Gillette, Caroline H. Roney, Orod Razeghi, …, Martin J. Bishop, …, Steven A. Niederer
The Effect of Ventricular Myofibre Orientation on Atrial Dynamics
Lecture notes in computer science, 2021
Marianne Beach, Iain Sim, Arihant Mehta, Irum Kotadia, Daniel O’Hare, …, Jose Alonso Solis-Lemus, Orod Razeghi, …, Steven A. Niederer, Caroline H. Roney
Using the Universal Atrial Coordinate System for MRI and Electroanatomic Data Registration in Patient-Specific Left Atrial Model Construction and Simulation
Lecture notes in computer science, 2021
Hao Xu, Steven A. Niederer, Steven E. Williams, David E. Newby, Michelle C. Williams, Alistair A. Young
Whole Heart Anatomical Refinement from CCTA Using Extrapolation and Parcellation
Lecture notes in computer science, 2021
Mirabeau Saha, Caroline Roney, Feng Xiong, Hubert Cochet, Stephanie Tan, steven niederer, Edward Vigmond, …
Constructing Realistic Canine Bilayer Biatrial Mesh for the Modeling and Simulation of Atria Fibrillation
Computing in cardiology, 2020
Caroline Roney, Marianne Beach, Arihant Mehta, Iain Sim, Cesare Corrado, Rokas Bendikas, Jose Alonso Solis-Lemus, Orod Razeghi, …, steven niederer
Constructing Virtual Patient Cohorts for Simulating Atrial Fibrillation Ablation
Computing in cardiology, 2020
Marina Strocchi, Aurel Neic, Matthias Gsell, Christoph Augustin, Julien Bouyssier, …, Martin Bishop, …, Steven Niederer
His Bundle Pacing but not Left Bundle Pacing Corrects Septal Flash in Left Bundle Branch Block Patients
Computing in cardiology, 2020
Damiano Fassina, Caroline Mendonca Costa, Sian Harding, steven niederer, Stefano Longobardi
Modelling the Effects of Conductive Polymers and Stem Cells Derived Myocytes on Scarred Heart Tissue
Computing in cardiology, 2020
Yingjing Feng, Caroline Roney, Mélèze Hocini, steven niederer, Edward Vigmond
Robust Atrial Ectopic Beat Classification From Surface ECG Using Second-Order Blind Source Separation
Computing in cardiology, 2020
Jose Alonso Solis-Lemus, Orod Razeghi, Caroline Roney, Iain Sim, Rahul Mukherjee, Steven Williams, Mark O'Neill, steven niederer
Software Framework to Quantify Pulmonary Vein Isolation Atrium Scar Tissue
Computing in cardiology, 2020
Irum Kotadia, John Whitaker, Caroline Roney, Steven Niederer, Mark O’Neill, Martin Bishop, Matthew Wright
Anisotropic Cardiac Conduction
Arrhythmia & Electrophysiology Review, 2020
John Whitaker, Júlia Karády, Rashed Karim, Catalina Tobon-Gomez, Thomas Fastl, Orod Razeghi, …, Cesare Corrado, …, Steven Niederer
Standardised computed tomographic assessment of left atrial morphology and tissue thickness in humans
IJC Heart & Vasculature, 2020
Cesare Corrado, Steven Williams, Caroline Roney, Gernot Plank, Mark O’Neill, Steven Niederer
Using machine learning to identify local cellular properties that support re-entrant activation in patient-specific models of atrial fibrillation
EP Europace, 2020
Eric C. Kerrigan, Yuanbo Nie, Omar Faqir, Caroline H. Kennedy, Steven A. Niederer, Jose A. Solis-Lemus, Peter Vincent, …
Direct Transcription for Dynamic Optimization: A Tutorial with a Case Study on Dual-Patient Ventilation During the COVID-19 Pandemic
Proceedings of the IEEE Conference on Decision & Control, including the Symposium on Adaptive Processes, 2020
Caroline Mendonca Costa, Caroline Roney, Marina Strocchi, Orod Razeghi, Steven Niederer
Clinical translation of patient-specific organ level cardiac models
Institute of Physics eBooks, 2020
Orod Razeghi, Iain Sim, Caroline H. Roney, Rashed Karim, Henry Chubb, John Whitaker, …, Steven Niederer
Fully Automatic Atrial Fibrosis Assessment Using a Multilabel Convolutional Neural Network
Circulation Cardiovascular Imaging, 2020
Albert J. Rogers, Anojan Selvalingam, Mahmood I. Alhusseini, David E. Krummen, Cesare Corrado, Firas Abuzaid, …, Steven Niederer, …
Machine Learned Cellular Phenotypes in Cardiomyopathy Predict Sudden Death
Circulation Research, 2020
Nathalie Selevsek, Florian Caiment, Ramona Nudischer, Hans Gmuender, Irina Agarkova, …, Alex Lewalle, …, Steven Niederer, …
Network integration and modelling of dynamic drug responses at multi-omics levels
Communications Biology, 2020
Cesare Corrado, Adelisa Avezzù, Angela W. C. Lee, Caroline Mendoca Costa, Caroline H. Roney, Marina Strocchi, Martin Bishop, Steven A. Niederer
Using cardiac ionic cell models to interpret clinical data
WIREs Mechanisms of Disease, 2020
Caroline H. Roney, Marianne L. Beach, Arihant M. Mehta, Iain Sim, Cesare Corrado, Rokas Bendikas, Jose A. Solis-Lemus, Orod Razeghi, …, Steven A. Niederer
In silico Comparison of Left Atrial Ablation Techniques That Target the Anatomical, Structural, and Electrical Substrates of Atrial Fibrillation
Frontiers in Physiology, 2020
José A. Solís-Lemus, Edward Costar, Denis Doorly, Eric C. Kerrigan, Caroline H. Kennedy, …, Steven Niederer, …
A simulated single ventilator/dual patient ventilation strategy for acute respiratory distress syndrome during the COVID-19 pandemic
Royal Society Open Science, 2020
Steven Niederer, Bradley Porter, C. Aldo Rinaldi
To the Editor — Multisite pacing strategies: Solutions looking for a problem?
Heart Rhythm O2, 2020
Orod Razeghi, Marina Strocchi, Angela Lee, Stefano Longobardi, Baldeep S. Sidhu, Justin Gould, Jonathan M. Behar, Ronak Rajani, …, Steven A. Niederer
Tracking the motion of intracardiac structures aids the development of future leadless pacing systems
Journal of Cardiovascular Electrophysiology, 2020
Orod Razeghi, José Alonso Solís-Lemus, Angela W.C. Lee, Rashed Karim, Cesare Corrado, Caroline H. Roney, Adelaide de Vecchi, Steven A. Niederer
CemrgApp: An interactive medical imaging application with image processing, computer vision, and machine learning toolkits for cardiovascular research
SoftwareX, 2020
Baldeep Singh Sidhu, Tiago Rua, Justin Gould, Bradley Porter, Benjamin Sieniewicz, Steven Niederer, …
Economic evaluation of a dedicated cardiac resynchronisation therapy preassessment clinic
Open Heart, 2020
Marina Strocchi, Angela W.C. Lee, Aurel Neic, Julien Bouyssier, Karli Gillette, Gernot Plank, …, Martin J. Bishop, …, Steven A. Niederer
His-bundle and left bundle pacing with optimized atrioventricular delay achieve superior electrical synchrony over endocardial and epicardial pacing in left bundle branch block patients
Heart Rhythm, 2020
Marina Strocchi, Christoph M. Augustin, Matthias A. F. Gsell, Elias Karabelas, Aurel Neic, Karli Gillette, Orod Razeghi, …, Martin J. Bishop, …, Steven A. Niederer
A publicly available virtual cohort of four-chamber heart meshes for cardiac electro-mechanics simulations
PLoS ONE, 2020
Caroline Mendonca Costa, Aurel Neic, Gernot Plank, Eric Kerfoot, Bradley Porter, …, Martin Bishop, Steven Niederer
Building Models of Patient-Specific Anatomy and Scar Morphology from Clinical MRI Data
Systems Medicine, 2020
C Mendonca Costa, A Neic, K Gillette, B Porter, J Gould, …, M J Bishop, S A Niederer
P532Endocardial pacing is less arrhythmogenic than conventional epicardial pacing when pacing in proximity to scar in patients with ischemic heart failure
EP Europace, 2020
L O’neill, I Sim, D O’hare, J Whitaker, R Mukherjee, C Roney, O Razeghi, S Niederer, …
P920Understanding arrhythmia mechanisms in patients with atrial septal defects
EP Europace, 2020
Justin Gould, Bradley Porter, Baldeep S. Sidhu, Simon Claridge, Zhong Chen, …, Fernando O. Campos, Martin J. Bishop, Caroline Mendonca Costa, Steven Niederer, …
High mean entropy calculated from cardiac MRI texture analysis is associated with antitachycardia pacing failure
Pacing and Clinical Electrophysiology, 2020
Caroline H. Roney, Rokas Bendikas, Farhad Pashakhanloo, Cesare Corrado, Edward J. Vigmond, Elliot R. McVeigh, …, Steven A. Niederer
Constructing a Human Atrial Fibre Atlas
Annals of Biomedical Engineering, 2020
Helder Pereira, Steven Niederer, Christopher A Rinaldi
Electrocardiographic imaging for cardiac arrhythmias and resynchronization therapy
EP Europace, 2020
S. A. Niederer, Y. Aboelkassem, C. D. Cantwell, C. Corrado, S. Coveney, E. M. Cherry, …, M. Riabiz, C. H. Roney, …
Creation and application of virtual patient cohorts of heart models
Philosophical Transactions of the Royal Society A Mathematical Physical and Engineering Sciences, 2020
Sam Coveney, Cesare Corrado, Caroline H. Roney, Daniel O’Hare, Steven E. Williams, Mark D. O’Neill, Steven A. Niederer, Richard H. Clayton, …
Gaussian process manifold interpolation for probabilistic atrial activation maps and uncertain conduction velocity
Philosophical Transactions of the Royal Society A Mathematical Physical and Engineering Sciences, 2020
S. Longobardi, A. Lewalle, S. Coveney, I. Sjaastad, E. K. S. Espe, W. E. Louch, …, S. A. Niederer
Predicting left ventricular contractile function via Gaussian process emulation in aortic-banded rats
Philosophical Transactions of the Royal Society A Mathematical Physical and Engineering Sciences, 2020
Gary R. Mirams, Steven A. Niederer, Richard H. Clayton
The fickle heart: uncertainty quantification in cardiac and cardiovascular modelling and simulation
Philosophical Transactions of the Royal Society A Mathematical Physical and Engineering Sciences, 2020
Caroline Mendonca Costa, Grace C. Anderson, Veronique M. F. Meijborg, Christopher O’Shea, Michael J. Shattock, …, Steven Niederer, …
The Amplitude-Normalized Area of a Bipolar Electrogram as a Measure of Local Conduction Delay in the Heart
Frontiers in Physiology, 2020
Mark K. Elliott, Vishal Mehta, Baldeep Singh Sidhu, Steven Niederer, Christopher A. Rinaldi
Electrocardiographic imaging of His bundle, left bundle branch, epicardial, and endocardial left ventricular pacing to achieve cardiac resynchronization therapy
HeartRhythm Case Reports, 2020
Baldeep S. Sidhu, Justin Gould, Bradley Porter, Mark Elliott, Vishal Mehta, Steven Niederer, …
Completely Leadless Cardiac Resynchronization Defibrillator System
JACC. Clinical electrophysiology, 2020
Baldeep S. Sidhu, Bradley Porter, Justin Gould, Benjamin Sieniewicz, Mark Elliott, …, Steven Niederer, …
Leadless left ventricular endocardial pacing in nonresponders to conventional cardiac resynchronization therapy
Pacing and Clinical Electrophysiology, 2020
Caroline Mendonca Costa, Aurel Neic, Karli Gillette, Bradley Porter, Justin Gould, …, Martin J. Bishop, Steven A. Niederer
Left ventricular endocardial pacing is less arrhythmogenic than conventional epicardial pacing when pacing in proximity to scar
Heart Rhythm, 2020
Kiarash Tazmini, Michael Frisk, Alexandre Lewalle, Martin Laasmaa, Stefano Morotti, David B. Lipsett, …, Steven A. Niederer, …
Hypokalemia Promotes Arrhythmia by Distinct Mechanisms in Atrial and Ventricular Myocytes
Circulation Research, 2020
Jorge Corral-Acero, Francesca Margara, Maciej Marciniak, Cristobal Rodero, Filip Loncaric, Yingjing Feng, …, Steven Niederer, …
The ‘Digital Twin’ to enable the vision of precision cardiology
European Heart Journal, 2020
Stefano Longobardi, Alexandre Lewalle, Cynthia J. Musante, Anna Sher, Steven A. Niederer
Quantifying Contributions of Cellular Mechanical Myocardial Properties on Left Ventricular Contractile Function in Aortic Banded Rats
Biophysical Journal, 2020
Marina Strocchi, Matthias A.F. Gsell, Christoph M. Augustin, Orod Razeghi, Caroline H. Roney, Anton J. Prassl, Edward J. Vigmond, …, Martin J. Bishop, …, Steven A. Niederer
Simulating ventricular systolic motion in a four-chamber heart model with spatially varying robin boundary conditions to model the effect of the pericardium
Journal of Biomechanics, 2020
Stuart G. Campbell, Steven A. Niederer
KBTBD13 and the ever-expanding sarcomeric universe
Journal of Clinical Investigation, 2020
Mirabeau Saha, Caroline Roney, Hubert Cochet, steven niederer, Edward Vigmond, Stanley Nattel
Myocardial Transmural Electrical Disruption Affects Electrogram Pattern
Computing in cardiology, 2019
Cesare Corrado, Orod Razeghi, Caroline Roney, Sam Coveney, Steven Williams, Iain Sim, Mark O’Neill, …, Steven Niederer
Quantifying atrial anatomy uncertainty from clinical data and its impact on electro-physiology simulation predictions
Medical Image Analysis, 2019
Christoph M. Augustin, Thomas E. Fastl, Aurel Neic, Chiara Bellini, John Whitaker, …, Martin J. Bishop, …, Steven A. Niederer
The impact of wall thickness and curvature on wall stress in patient-specific electromechanical models of the left atrium
Biomechanics and Modeling in Mechanobiology, 2019
Helder Pereira, Tom A. Jackson, Simon Claridge, Cheng Yao, Benjamin Sieniewicz, …, Steven Niederer, …
Evidence of reverse electrical remodelling by non-invasive electrocardiographic imaging to assess acute and chronic changes in bulk ventricular activation following cardiac resynchronisation therapy
Journal of Electrocardiology, 2019
Xinyang Li, Caroline H. Roney, Balvinder S. Handa, Rasheda A. Chowdhury, Steven A. Niederer, Nicholas S. Peters, Fu Siong Ng
Standardised Framework for Quantitative Analysis of Fibrillation Dynamics
Scientific Reports, 2019
Angela W.C. Lee, Declan P. O'Regan, Justin Gould, Baldeep Sidhu, Benjamin Sieniewicz, …, Steven A. Niederer
Sex-Dependent QRS Guidelines for Cardiac Resynchronization Therapy Using Computer Model Predictions
Biophysical Journal, 2019
Liuyang Feng, Hao Gao, Boyce Griffith, Steven Niederer, Xiaoyu Luo
Analysis of a coupled fluid‐structure interaction model of the left atrium and mitral valve
International Journal for Numerical Methods in Biomedical Engineering, 2019
Waqar Aziz, Simon Claridge, Ioannis Ntalas, Justin Gould, Adelaide de Vecchi, Orod Razeghi, …, Steven Niederer, …
Emerging Role of Cardiac Computed Tomography in Heart Failure
ESC Heart Failure, 2019
Henry Chubb, Rashed Karim, Rahul Mukherjee, Steven E. Williams, John Whitaker, …, Steven A. Niederer, …
A comprehensive multi‐index cardiac magnetic resonance‐guided assessment of atrial fibrillation substrate prior to ablation: Prediction of long‐term outcomes
Journal of Cardiovascular Electrophysiology, 2019
Alexandre Lewalle, Sander Land, Jort J. Merken, Anne Raafs, Pilar Sepúlveda, …, Steven A. Niederer
Balance of Active, Passive, and Anatomical Cardiac Properties in Doxorubicin-Induced Heart Failure
Biophysical Journal, 2019
Baldeep Singh Sidhu, Angela W C Lee, Ulrike Haberland, Ronak Rajani, Steven Niederer, Christopher Aldo Rinaldi
Combined computed tomographic perfusion and mechanics with predicted activation pattern can successfully guide implantation of a wireless endocardial pacing system
EP Europace, 2019
Anne-Marie Plancke, Adam Connolly, Philip M. Gemmell, Aurel Neic, Luke C. McSpadden, John Whitaker, …, Steven A. Niederer, …, Martin J. Bishop
Generation of a cohort of whole-torso cardiac models for assessing the utility of a novel computed shock vector efficiency metric for ICD optimisation
Computers in Biology and Medicine, 2019
Louisa O’Neill, Rashed Karim, Rahul K Mukherjee, John Whitaker, Iain Sim, …, Orod Razeghi, Steven Niederer, …
Pulmonary vein encirclement using an Ablation Index-guided point-by-point workflow: cardiovascular magnetic resonance assessment of left atrial scar formation
EP Europace, 2019
A.W.C. Lee, U.C. Nguyen, O. Razeghi, J. Gould, B.S. Sidhu, B. Sieniewicz, …, S. Niederer
A rule-based method for predicting the electrical activation of the heart with cardiac resynchronization therapy from non-invasive clinical data
Medical Image Analysis, 2019
T. Jackson, S. Claridge, J. Behar, B. Sieniewicz, J. Gould, …, A. Lee, S. Niederer, …
Differential effect with septal and apical RV pacing on ventricular activation in patients with left bundle branch block assessed by non-invasive electrical imaging and in silico modelling
Journal of Interventional Cardiac Electrophysiology, 2019
Iain Sim, Orod Razeghi, Rashed Karim, Henry Chubb, John Whitaker, Louisa O’Neill, …, Caroline H. Roney, …, Steven Niederer, …
Reproducibility of Atrial Fibrosis Assessment Using CMR Imaging and an Open Source Platform
JACC. Cardiovascular imaging, 2019
Rahul K Mukherjee, Caroline Mendonca Costa, Radhouene Neji, James L Harrison, Iain Sim, Steven E Williams, …, Steven A Niederer, …
Evaluation of a real-time magnetic resonance imaging-guided electrophysiology system for structural and electrophysiological ventricular tachycardia substrate assessment
EP Europace, 2019
Steven E. Williams, Louisa O’Neill, Caroline H. Roney, Justo Julia, Andreas Metzner, Bruno Reißmann, …, Steven Niederer, …
Left atrial effective conducting size predicts atrial fibrillation vulnerability in persistent but not paroxysmal atrial fibrillation
Journal of Cardiovascular Electrophysiology, 2019
Sam Coveney, Richard H. Clayton, Cesare Corrado, Caroline H. Roney, Richard D. Wilkinson, Jeremy E. Oakley, Finn Lindgren, …, Steven A. Niederer
Probabilistic Interpolation of Uncertain Local Activation Times on Human Atrial Manifolds
IEEE Transactions on Biomedical Engineering, 2019
Caroline H. Roney, Ali Pashaei, Marianna Meo, Rémi Dubois, Patrick M. Boyle, …, Steven A. Niederer, …
Universal atrial coordinates applied to visualisation, registration and construction of patient specific meshes
Medical Image Analysis, 2019
Caroline Mendonca Costa, Aurel Neic, Eric Kerfoot, Bradley Porter, Benjamin Sieniewicz, …, Martin J. Bishop, Steven A. Niederer
Pacing in proximity to scar during cardiac resynchronization therapy increases local dispersion of repolarization and susceptibility to ventricular arrhythmogenesis
Heart Rhythm, 2019
Justin Gould, Bradley Porter, Simon Claridge, Zhong Chen, Benjamin J. Sieniewicz, …, Steven Niederer, Martin J. Bishop, …
Mean entropy predicts implantable cardioverter-defibrillator therapy using cardiac magnetic resonance texture analysis of scar heterogeneity
Heart Rhythm, 2019
Helder Pereira, Tom A. Jackson, Simon Claridge, Jonathan M. Behar, Cheng Yao, …, Steven Niederer, …
Comparison of Echocardiographic and Electrocardiographic Mapping for Cardiac Resynchronisation Therapy Optimisation
Cardiology Research and Practice, 2019
Benjamin J. Sieniewicz, Tom Jackson, Simon Claridge, Helder Pereira, Justin Gould, …, Steve Niederer, …
Optimization of CRT programming using non‐invasive electrocardiographic imaging to assess the acute electrical effects of multipoint pacing
Journal of Arrhythmia, 2019
Coen de Vente, Mitko Veta, Orod Razeghi, Steven Niederer, Josien Pluim, Kawal Rhode, Rashed Karim
Convolutional Neural Networks for Segmentation of the Left Atrium from Gadolinium-Enhancement MRI Images
Lecture notes in computer science, 2019
John Whitaker, Radhouene Neji, Nicholas Byrne, Esther Puyol-Antón, Rahul K. Mukherjee, …, Orod Razeghi, …, Steven Niederer, …, Martin J. Bishop, …
Improved co-registration of ex-vivo and in-vivo cardiovascular magnetic resonance images using heart-specific flexible 3D printed acrylic scaffold combined with non-rigid registration
Journal of Cardiovascular Magnetic Resonance, 2019
Anastasia Nasopoulou, David A. Nordsletten, Steven A. Niederer, Pablo Lamata
Solution to the Unknown Boundary Tractions in Myocardial Material Parameter Estimations
Lecture notes in computer science, 2019
Cesare Corrado, Steven Williams, Iain Sim, Sam Coveney, Mark O'Neill, …, Steven Niederer
An Algorithm to Sample an Anatomy With Uncertainty
Computing in cardiology, 2018
Caroline Mendonca Costa, Aurel Neic, Gernot Plank, Eric Kerfoot, Bradley Porter, …, Martin J. Bishop, Steven A. Niederer
Personalized Modelling Pipeline for Cardiac Electrophysiology Simulations of Cardiac Resynchronization Therapy in Infarct patients
Computing in cardiology, 2018
Angela Lee, Uyen Chau Nguyen, Justin Gould, Baldeep Sidhu, Benjamin Sieniewicz, Caroline Mendonca Costa, …, Steven Niederer
Predicting Activation Patterns in Cardiac Resynchronization Therapy Patients
Computing in cardiology, 2018
A. De Vecchi, S. Niederer, R. Rajani, S. Redwood, B. Prendergast
Individual Patient-specific Planning of Minimally Invasive Transcatheter Intervention for Heart Valve Disease
EClinicalMedicine, 2018
Steven A. Niederer, Kenneth S. Campbell, Stuart G. Campbell
A short history of the development of mathematical models of cardiac mechanics
Journal of Molecular and Cellular Cardiology, 2018
Caroline H. Roney, John Whitaker, Iain Sim, Louisa O'Neill, Rahul K. Mukherjee, Orod Razeghi, …, Steven A. Niederer
A technique for measuring anisotropy in atrial conduction to estimate conduction velocity and atrial fibre direction
Computers in Biology and Medicine, 2018
Steven Niederer, Anna Sher
Quantitative Systems Pharmacology: Modelling and simulating drug action in health and disease
Progress in Biophysics and Molecular Biology, 2018
Steven A. Niederer, Joost Lumens, Natalia A. Trayanova
Computational models in cardiology
Nature Reviews Cardiology, 2018
Åsmund T Røe, Marianne Ruud, Emil K Espe, Ornella Manfra, Stefano Longobardi, Jan M Aronsen, …, Steven A Niederer, …
Regional diastolic dysfunction in post-infarction heart failure: role of local mechanical load and SERCA expression
Cardiovascular Research, 2018
Adelaide De Vecchi, David Marlevi, David A. Nordsletten, Ioannis Ntalas, Jonathon Leipsic, …, Steven A. Niederer
Left ventricular outflow obstruction predicts increase in systolic pressure gradients and blood residence time after transcatheter mitral valve replacement
Scientific Reports, 2018
Caroline H Roney, Steven E Williams, Hubert Cochet, Rahul K Mukherjee, Louisa O’Neill, …, Orod Razeghi, …, Steven A Niederer
Patient-specific simulations predict efficacy of ablation of interatrial connections for treatment of persistent atrial fibrillation
EP Europace, 2018
Caroline H Roney, Fu Siong Ng, Michael T Debney, Christian Eichhorn, Arun Nachiappan, …, Steven A Niederer, …
Determinants of new wavefront locations in cholinergic atrial fibrillation
EP Europace, 2018
Louisa O’Neill, Steven E. Williams, John Whitaker, Iain Sim, Rahul Mukherjee, …, Steven Niederer, …
94Characterisation of arrhythmia triggers in atrial septal defects: Patterns of atrial ectopy on continuous holter monitoring
EP Europace, 2018
Bernardo L. de Oliveira, Steven A. Niederer
A new paradigm for the assessment of chronic anthracycline mitochondrial cardiotoxicity
Journal of Pharmacological and Toxicological Methods, 2018
Benjamin J. Sieniewicz, Tom Jackson, Simon Claridge, Helder Pereira, Justin Gould, …, Steve Niederer, …
Variation in activation time during bipolar vs extended bipolar left ventricular pacing
Journal of Cardiovascular Electrophysiology, 2018
Benjamin J. Sieniewicz, Justin Gould, Bradley Porter, Baldeep S Sidhu, Jonathan M Behar, …, Steve Niederer, …
Optimal site selection and image fusion guidance technology to facilitate cardiac resynchronization therapy
Expert Review of Medical Devices, 2018
Balvinder S. Handa, Caroline H. Roney, Charles Houston, Norman A. Qureshi, Xinyang Li, David S. Pitcher, …, Steven A. Niederer, …
Analytical approaches for myocardial fibrillation signals
Computers in Biology and Medicine, 2018
Ioannis Ntalas, Steven Niederer, Waqar Aziz, John B. Chambers, Ronak Rajani
Giant left atrium: Adaptive or maladaptive?
Hellenic Journal of Cardiology, 2018
Steven A. Niederer, Christopher A. Rinaldi
Is CRT response rate all about patient selection?
International Journal of Cardiology, 2018
Nicholas Child, Richard H. Clayton, Caroline H. Roney, Jacob I. Laughner, Allan Shuros, Petr Neuzil, …, Steven A. Niederer, …
Unraveling the Underlying Arrhythmia Mechanism in Persistent Atrial Fibrillation
Circulation Arrhythmia and Electrophysiology, 2018
Marcha Verheijen, Yannick Schrooders, Hans Gmuender, Ramona Nudischer, Olivia Clayton, …, Steven Niederer, …
Bringing in vitro analysis closer to in vivo: Studying doxorubicin toxicity and associated mechanisms in 3D human microtissues with PBPK-based dose modelling
Toxicology Letters, 2018
Helder Pereira, Tom A. Jackson, Benjamin Sieniewicz, Justin Gould, Cheng Yao, Steven Niederer, …
Non-invasive electrophysiological assessment of the optimal configuration of quadripolar lead vectors on ventricular activation times
Journal of Electrocardiology, 2018
Benjamin J. Sieniewicz, Jonathan M. Behar, Justin Gould, Simon Claridge, Bradley Porter, …, Steve Niederer, …
Guidance for Optimal Site Selection of a Leadless Left Ventricular Endocardial Electrode Improves Acute Hemodynamic Response and Chronic Remodeling
JACC. Clinical electrophysiology, 2018
Cesare Corrado, Steven Williams, Rashed Karim, Gernot Plank, Mark O’Neill, Steven Niederer
A work flow to build and validate patient specific left atrium electrophysiology models from catheter measurements
Medical Image Analysis, 2018
Louisa O’Neill, James Harrison, Henry Chubb, John Whitaker, Rahul K Mukherjee, …, Steven Niederer, …
Voltage and pace-capture mapping of linear ablation lesions overestimates chronic ablation gap size
EP Europace, 2018
Benjamin J Sieniewicz, Jonathan M Behar, Manav Sohal, Justin Gould, Simon Claridge, …, Steve Niederer, …
Electrical latency predicts the optimal left ventricular endocardial pacing site: results from a multicentre international registry
EP Europace, 2018
Tom Banks, Orod Razeghi, Ioannis Ntalas, Waqar Aziz, Jonathan M. Behar, Rebecca Preston, …, Steven Niederer, …
Automated quantification of mitral valve geometry on multi-slice computed tomography in patients with dilated cardiomyopathy – Implications for transcatheter mitral valve replacement
Journal of cardiovascular computed tomography, 2018
Caroline Mendonca Costa, Gernot Plank, Christopher A. Rinaldi, Steven A. Niederer, Martin J. Bishop
Modeling the Electrophysiological Properties of the Infarct Border Zone
Frontiers in Physiology, 2018
Thomas E. Fastl, Catalina Tobon-Gomez, Andrew Crozier, John Whitaker, Ronak Rajani, …, Martin J. Bishop, Steven A. Niederer
Personalized computational modeling of left atrial geometry and transmural myofiber architecture
Medical Image Analysis, 2018
Simon Claridge, Natalia Briceno, Zhong Chen, Kalpa De Silva, Bhavik Modi, …, Steven Niederer, …
Changes in contractility determine coronary haemodynamics in dyssynchronous left ventricular heart failure, not vice versa
IJC Heart & Vasculature, 2018
John Whitaker, Jeffrey Fish, James Harrison, Henry Chubb, Steven E. Williams, …, Cesare Corrado, …, Steve Niederer, …
Lesion Index–Guided Ablation Facilitates Continuous, Transmural, and Durable Lesions in a Porcine Recovery Model
Circulation Arrhythmia and Electrophysiology, 2018
David R. Warriner, Tom Jackson, Ernesto Zacur, Eva Sammut, Paul Sheridan, …, Steve Alexander Niederer, …
An Asymmetric Wall-Thickening Pattern Predicts Response to Cardiac Resynchronization Therapy
JACC. Cardiovascular imaging, 2018
B Sieniewicz, J Behar, M Sohal, S Claridge, B Porter, S Niederer, …
533Does targeting the site of maximal electrical delay result in the optimal haemodynamic improvement; results from an international multi-centre registry
EP Europace, 2018
J Gould, J Behar, R Rajani, B Sieniewicz, B Porter, …, O Razeghi, S Niederer, …
P333Dual energy cardiac computed tomography to guide cardiac resynchronisation therapy: a feasibility study using coronary venous anatomy, scar and strain to guide optimal left ventricular lead placement
EP Europace, 2018
Alexandre Lewalle, Sander Land, Eric Carruth, Lawrence R. Frank, Pablo Lamata, …, Steven A. Niederer, …
Decreasing Compensatory Ability of Concentric Ventricular Hypertrophy in Aortic-Banded Rat Hearts
Frontiers in Physiology, 2018
Angela W C Lee, Caroline Mendonca Costa, Marina Strocchi, Christopher A Rinaldi, Steven A Niederer
Computational Modeling for Cardiac Resynchronization Therapy
Journal of Cardiovascular Translational Research, 2018
Júlia Karády, Ioannis Ntalas, Bernard Prendergast, Christopher Blauth, Steven Niederer, Pál Maurovich-Horvat, …
Transcatheter mitral valve replacement in mitral annulus calcification – “The art of computer simulation”
Journal of cardiovascular computed tomography, 2018
M Fernandez‐Chas, M J Curtis, S A Niederer
Mechanism of doxorubicin cardiotoxicity evaluated by integrating multiple molecular effects into a biophysical model
British Journal of Pharmacology, 2017
Adelaide de Vecchi, Steven Niederer, Júlia Karády, Ioannis Ntalas, Pál Maurovich-Horvat, Ronak Rajani
Computational fluid dynamic modelling to determine the hemodynamic effects of implanting a transcatheter mitral valve within the left ventricle
International journal of cardiac imaging, 2017
Bernardo de Oliveira, Steven Niederer
Computational Models for Acute and Chronic Doxorubicin Mitochondrial Cardiotoxicity
Journal of Pharmacological and Toxicological Methods, 2017
S A Niederer, J Gould, B Sieniewicz, F Prinzen, C A Rinaldi
Is the rapidly paced pig the optimal model for endocardial cardiac resynchronization therapy?
EP Europace, 2017
Sander Land, Steven Alexander Niederer
Influence of atrial contraction dynamics on cardiac function
International Journal for Numerical Methods in Biomedical Engineering, 2017
John Whitaker, Sandeep Panikker, Thomas Fastl, Cesare Corrado, Renu Virmani, Robert Kutys, …, Steven Niederer, …
Cardiac CT assessment of tissue thickness at the ostium of the left atrial appendage predicts acute success of radiofrequency ablation
Pacing and Clinical Electrophysiology, 2017
Orod Razeghi, Rashed Karim, John Whitaker, Catalina Tobon Gomez, Steven Niederer
A Platform for Quantifying Atrial Structural Remodelling
Computing in cardiology, 2017
Cesare Corrado, Steven Williams, Gernot Plank, Mark O�Neill, Steven Niederer
A Predictive Personalised Model for the Left Atrium
Computing in cardiology, 2017
Tobias H. Dovmark, Alzbeta Hulikova, Steven A. Niederer, Richard D. Vaughan‐Jones, Pawel Swietach
Normoxic cells remotely regulate the acid‐base balance of cells at the hypoxic core of connexin‐coupled tumor growths
The FASEB Journal, 2017
Lars Kuepfer, Olivia Clayton, Christoph Thiel, Henrik Cordes, Ramona Nudischer, …, Steven Niederer, …
A model-based assay design to reproduce in vivo patterns of acute drug-induced toxicity
Archives of Toxicology, 2017
Antonios P. Antoniadis, Jonathan M. Behar, Ben Sieniewicz, Justin Gould, Steven Niederer, Christopher A. Rinaldi
A comparison of the different features of quadripolar left ventricular pacing leads to deliver cardiac resynchronization therapy
Expert Review of Medical Devices, 2017
Steven E Williams, Nick Linton, Louisa O'Neill, James Harrison, John Whitaker, …, Steven Niederer, …
The effect of activation rate on left atrial bipolar voltage in patients with paroxysmal atrial fibrillation
Journal of Cardiovascular Electrophysiology, 2017
Aurel Neic, Fernando O. Campos, Anton J. Prassl, Steven A. Niederer, Martin J. Bishop, Edward J. Vigmond, Gernot Plank
Efficient computation of electrograms and ECGs in human whole heart simulations using a reaction-eikonal model
Journal of Computational Physics, 2017
B Ribba, HP Grimm, B Agoram, MR Davies, K Gadkar, S Niederer, …
Methodologies for Quantitative Systems Pharmacology (QSP) Models: Design and Estimation
CPT Pharmacometrics & Systems Pharmacology, 2017
Steven A. Niederer, Bernardo L. de Oliveira, Michael J. Curtis
The opportunities and challenges for biophysical modelling of beneficial and adverse drug actions on the heart
Current Opinion in Systems Biology, 2017
Zhong Chen, Steve Niederer, Nesan Shanmugam, Maxime Sermesant, Christopher A. Rinaldi
Cardiac computational modeling of ventricular tachycardia and cardiac resynchronization therapy: a clinical perspective
Minerva Cardiology and Angiology, 2017
L. O'neill, S. Williams, N. Linton, J. Harrison, J. Whitaker, …, S. Niederer, …
P1589Left atrial bipolar voltage: dependence on activation rate
EP Europace, 2017
Sara Gattoni, Åsmund Treu Røe, Jan Magnus Aronsen, Ivar Sjaastad, William E. Louch, …, Steven A. Niederer
Compensatory and decompensatory alterations in cardiomyocyte Ca2+ dynamics in hearts with diastolic dysfunction following aortic banding
The Journal of Physiology, 2017
Jonathan M. Behar, Ronak Rajani, Amir Pourmorteza, Rebecca Preston, Orod Razeghi, Steve Niederer, Shaumik Adhya, …
Comprehensive use of cardiac computed tomography to guide left ventricular lead placement in cardiac resynchronization therapy
Heart Rhythm, 2017
Steven E. Williams, Nick W.F. Linton, James Harrison, Henry Chubb, John Whitaker, …, Steven Niederer, …
Intra-Atrial Conduction Delay Revealed by Multisite Incremental Atrial Pacing is an Independent Marker of Remodeling in Human Atrial Fibrillation
JACC. Clinical electrophysiology, 2017
Sander Land, So-Jin Park-Holohan, Nicolas P. Smith, Cristobal G. dos Remedios, Jonathan C. Kentish, Steven A. Niederer
A model of cardiac contraction based on novel measurements of tension development in human cardiomyocytes
Journal of Molecular and Cellular Cardiology, 2017
Steven E Williams, James L Harrison, Henry Chubb, John Whitaker, Radek Kiedrowicz, …, Steven Niederer, …
Local activation time sampling density for atrial tachycardia contact mapping: how much is enough?
EP Europace, 2017
Alexandre Lewalle, Sander Land, Steven Niederer
Development of a Patient‐Based Computational Modeling Framework for Analyzing the Mechanisms of Doxorubicin Cardiotoxicity
The FASEB Journal, 2017
Michael J. Shattock, Kyung Chan Park, Hsiang-Yu Yang, Angela W. C. Lee, Steven Niederer, Kenneth T. MacLeod, James Winter
Restitution slope is principally determined by steady-state action potential duration
Cardiovascular Research, 2017
Anastasia Nasopoulou, Anoop Shetty, Jack Lee, David Nordsletten, C. Aldo Rinaldi, …, Steven Niederer
Improved identifiability of myocardial material parameters by an energy-based cost function
Biomechanics and Modeling in Mechanobiology, 2017
Anastasia Nasopoulou, David A. Nordsletten, Steven A. Niederer, Pablo Lamata
Feasibility of the Estimation of Myocardial Stiffness with Reduced 2D Deformation Data
Lecture notes in computer science, 2017
ANGELA W. C. LEE, ANDREW CROZIER, EOIN R. HYDE, PABLO LAMATA, MICHAEL TRUONG, …, STEVEN NIEDERER
Biophysical Modeling to Determine the Optimization of Left Ventricular Pacing Site and AV/VV Delays in the Acute and Chronic Phase of Cardiac Resynchronization Therapy
Journal of Cardiovascular Electrophysiology, 2016
Bernardo L. de Oliveira, Steven Niederer
A Biophysical Systems Approach to Identifying the Pathways of Acute and Chronic Doxorubicin Mitochondrial Cardiotoxicity
PLoS Computational Biology, 2016
Andrew Crozier, Bojan Blazevic, Pablo Lamata, Gernot Plank, Matthew Ginks, …, Steven A. Niederer, …
Analysis of lead placement optimization metrics in cardiac resynchronization therapy with computational modelling
EP Europace, 2016
Steven E Williams, Nick W F Linton, Steven Niederer, Mark D O'Neill
Simultaneous display of multiple three-dimensional electrophysiological datasets (dot mapping)
EP Europace, 2016
J.M. Evans, John Silberbauer, B. Glover, A. Kontogeorgis, A.J.A. McLellan, …, S. Niederer, …
ORAL ABSTRACTS (2)EP & Ablation19CARDIAC ABLATION PATIENT REPORTED OUTCOMES MEASURES (PROMS): ANALYSIS OF POST-ABLATION AND 1 YEAR FOLLOW-UP DATA20INTENTIONAL CORONARY VEIN EXIT AND CARBON DIOXIDE INSUFFLATION TO ALLOW SAFE SUBXIPHOID EPICARDIAL ACCESS FOR VENTRICULAR MAPPING AND ABLATION - FIRST EXPERIENCE21PACED FRACTIONATION DETECTION AS A TOOL FOR MAPPING SCARS IN VT22DOES USE OF CONTACT-FORCE SENSING CATHETERS IMPROVE THE OUTCOME OF ABLATION OF VENTRICULAR TACHYCARDIA?23RETROGRADE AORTIC ACCESS OF THE PULMONARY VENOUS ATRIUM PROVIDES EQUIVALENT OUTCOMES TO RIGHT ATRIAL OR TRANSEPTAL ACCESS OF THE LEFT ATRIUM IN PATIENTS WITH CONGENITAL HEART DISEASE24COMPUTATIONAL THREE-DIMENSION LEFT ATRIAL APPENDAGE WALL THICKNESS MAPS AND HISTOLOGICAL ANALYSIS TO GUIDE LEFT ATRIAL APPENDAGE ELECTRICAL ISOLATIONPacing & Devices25IDENTIFYING THE OPTIMAL LOCATION FOR LV ENDOCARIDAL PACING:RESULTS FROM A MULTICENTRE INTERNATIONAL REGISTRY OF LV ENDOCARDIAL PACING26UK MULTI-CENTRE REGISTRY OF TRANSVENOUS LEAD EXTRACTION: CLINICAL OUTCOME USING TRACTION, CUTTING SHEATHS AND LASER TECHNIQUES27SKIN FISTULA FORMATION - A NEW EXPERIENCE WITH THE NEW TYRX ABSORBABLE ANTIMICROVIAL ENVELOPE28BIFOCAL RIGHT VENTRICULAR PACING IN PATIENTS WITH FAILED CORONARY-SINUS LEAD IMPLANTS: LONG-TERM RESULTS FROM MULTICENTRE REGISTRY29REAL TIME X-MRI GUIDED LEFT VENTRICULAR LEAD IMPLANTATION FOR TARGETED DELIVERY OF CARDIAC RESYNCHRONIZATION THERAPY30ACUTE AND CHRONIC PERFORMANCE OF COMMUNICATING LEADLESS ANTI-TACHYCARDIA PACEMAKER AND SUBCUTANEOUS IMPLANTABLE DEFIBRILLATOR
EP Europace, 2016
Angela Lee, Manav Sohal, Jonathan Behar, Simon Claridge, Anoop Shetty, …, Steven Niederer
Personalised Biophysical Model to Optimise Left Ventricle Pacing Location for Cardiac Resynchronisation Therapy Over Time
Computing in cardiology, 2016
Thomas E Fastl, Catalina Tobon-Gomez, William A Crozier, John Whitaker, Ronak Rajani, …, Martin J Bishop, Steven A Niederer
Personalized Modeling Pipeline for Left Atrial Electromechanics
Computing in cardiology, 2016
Cesare Corrado, John Whitaker, Henry Chubb, Steven Williams, Matt Wright, …, Steven Niederer
Predicting Spiral Wave Stability by Personalized Electrophysiology Models
Computing in cardiology, 2016
Cesare Corrado, Steven A. Niederer
A two-variable model robust to pacemaker behaviour for the dynamics of the cardiac action potential
Mathematical Biosciences, 2016
Margarita Fernandez-Chas, Steven A. Niederer
An integrative biophysical model linking changes in protein function to emergent cellular phenotypes in left ventricular myocytes
Journal of Pharmacological and Toxicological Methods, 2016
Bernardo de Oliveira, Steven Niederer
Computational models of doxorubicin mitochondria cardiotoxicity
Journal of Pharmacological and Toxicological Methods, 2016
Jonathan M. Behar, Tom Jackson, Eoin Hyde, Simon Claridge, Jaswinder Gill, …, Steve Niederer, …
Optimized Left Ventricular Endocardial Stimulation Is Superior to Optimized Epicardial Stimulation in Ischemic Patients With Poor Response to Cardiac Resynchronization Therapy
JACC. Clinical electrophysiology, 2016
Zhong Chen, Ben Hanson, Manav Sohal, Eva Sammut, Tom Jackson, …, Steve Niederer, …
Coupling of ventricular action potential duration and local strain patterns during reverse remodeling in responders and nonresponders to cardiac resynchronization therapy
Heart Rhythm, 2016
John Whitaker, Ronak Rajani, Henry Chubb, Mark Gabrawi, Marta Varela, …, Steven Niederer, …
The role of myocardial wall thickness in atrial arrhythmogenesis
EP Europace, 2016
Cesare Corrado, John Whitaker, Henry Chubb, Steven Williams, Matthew Wright, …, Steven A. Niederer
Personalized Models of Human Atrial Electrophysiology Derived From Endocardial Electrograms
IEEE Transactions on Biomedical Engineering, 2016
Nicolas Smith, Steven Niederer
Is computational modeling adding value for understanding the Heart?
Journal of Molecular and Cellular Cardiology, 2016
Steven A. Niederer, Nic P. Smith
Using physiologically based models for clinical translation: predictive modelling, data interpretation or something in‐between?
The Journal of Physiology, 2016
EOIN R. HYDE, JONATHAN M. BEHAR, ANDREW CROZIER, SIMON CLARIDGE, TOM JACKSON, …, STEVEN A. NIEDERER, …
Improvement of Right Ventricular Hemodynamics with Left Ventricular Endocardial Pacing during Cardiac Resynchronization Therapy
Pacing and Clinical Electrophysiology, 2016
Sara Gattoni, Åsmund Treu Røe, Michael Frisk, William E. Louch, Steven A. Niederer, Nicolas P. Smith
The calcium–frequency response in the rat ventricular myocyte: an experimental and modelling study
The Journal of Physiology, 2016
Sander Land, Steven A. Niederer
Investigating Cooperativity using a New Biophysically Detailed Cardiac Contraction Model
Biophysical Journal, 2016
Corrado Cesare, Whitaker John, Chubb Henry, Williams Steven, Wright Matt, …, Niederer Steven
個別電気生理学モデルによるスパイラル波安定性の予測【Powered by NICT】
IEEE Conference Proceedings, 2016
Simon Claridge, Zhong Chen, Tom Jackson, Kalpa De Silva, Jonathan Behar, …, Steve Niederer, …
Effects of Epicardial and Endocardial Cardiac Resynchronization Therapy on Coronary Flow: Insights From Wave Intensity Analysis
Journal of the American Heart Association, 2015
Sander Land, Viatcheslav Gurev, Sander Arens, Christoph M. Augustin, Lukas Baron, …, Steven A. Niederer
Verification of cardiac mechanics software: benchmark problems and solutions for testing active and passive material behaviour
Proceedings of the Royal Society A Mathematical Physical and Engineering Sciences, 2015
Espen W. Remme, Steven Niederer, Ola Gjesdal, Kristoffer Russell, Eoin R. Hyde, Nicolas Smith, …
Factors determining the magnitude of the pre-ejection leftward septal motion in left bundle branch block
EP Europace, 2015
Alzbeta Hulikova, Richard D. Vaughan‐Jones, Steven A. Niederer, Pawel Swietach
CrossTalk opposing view: Physiological CO2 exchange does not normally depend on membrane channels
The Journal of Physiology, 2015
Pawel Swietach, Richard D. Vaughan‐Jones, Alzbeta Hulikova, Steven A. Niederer
Rebuttal from Pawel Swietach, Richard D. Vaughan‐Jones, Alzbeta Hulikova and Steven A. Niederer
The Journal of Physiology, 2015
Andrew Crozier, Bojan Blazevic, Pablo Lamata, Gernot Plank, Matthew Ginks, …, Steven A. Niederer
The relative role of patient physiology and device optimisation in cardiac resynchronisation therapy: A computational modelling study
Journal of Molecular and Cellular Cardiology, 2015
Christoph M. Augustin, Aurel Neic, Manfred Liebmann, Anton J. Prassl, Steven A. Niederer, Gundolf Haase, …
Anatomically accurate high resolution modeling of human whole heart electromechanics: A strongly scalable algebraic multigrid solver method for nonlinear deformation
Journal of Computational Physics, 2015
Steven Niederer, Cameron Walker, Andrew Crozier, Eoin R. Hyde, Bojan Blazevic, …
The impact of beat-to-beat variability in optimising the acute hemodynamic response in cardiac resynchronisation therapy
Clinical Trials and Regulatory Science in Cardiology, 2015
J.M. Behar, J.M. Behar, R. Providência, P.L. Cronbach, S. Siddiqui, …, S. Niederer, …, C.H. Roney, …
Devices & Sudden death31Quadripolar left ventricular leads should be the gold standard in crt due to efficacy and cost effectiveness: an analysis from a multi-centre uk registry32Cardiac computed tomography is a feasible imaging modality for pre procedural planning in patients undergoing upgrade from pacemakers to CRT33Derivation and external validation of a cardiac resynchronization therapy response score34Generation and validation of transformation coefficients to reconstruct 12-lead electrocardiograms from 3 subcutaneous implantable cardioverter defibrillator electrodes35Risk stratification of sudden cardiac death: positive evaluation of novel surface electrocardiogram biomarkers in a brugada syndrome cohort36The real world cost of cardiac implantable electronic device transvenous extractions37Advances in technology for rapid and reliable ecg acquisition38Excellent symptom rhythm correlation in patients with palpitations using a novel smartphone based event recorder39Differential ventricular repolarisation responses during sympathetic surge versus sustained sympathetic stimulation–in vivo evidence from humans40Approaching a fluro free daily life ep lab41Development and validation of the cardiff cardiac ablation prom (C-CAP) for patients with symptomatic cardiac arrhythmias42The changing tide of novel oral anti-coagulant use in england:
EP Europace, 2015
P.M. Heck, V. Luther, V. Luther, S.E. Williams, A.A. Schricker, …, S.A. Niederer, …
Mapping & Ablation19Novel global ultrasound imaging and continuous dipole density mapping: initial findings in AF patients20Low voltage functional myocardium is critical in determining the substrate of post-ablation atrial tachycardia: results from a prospective study using ripple mapping distinguishing low-voltage scar from conducting tissue21Ripple mapping of post infarct ventricular scar to identify conduction channels and guide substrate based ablation22Effect of chamber geometry and activation pattern on optimal local activation time sampling density for tachycardia diagnosis25Clinical measures of good basket placement predict successful outcome from atrial fibrillation rotor ablation26Unipolar electrogram amplitude is reduced at rotor sites critical to focal termination of human persistent AF27Cryoballoon versus point by point radiofrequency ablation or a novel combined approach: long term follow up and comparison of patterns of pulmonary vein reconnection between different ablation strategies in a randomised controlled trial28Recurrent high dominant frequency patterns in persistent atrial fibrillation29Optimisation of late gadolinium enhanced (LGE) cmr imaging of atrial ablation scar30Hyperacute and chronic changes in cerebral magnetic resonance images after PVAC, NMARQ and epicardial thoracoscopic surgical ablation for paroxysmal atrial fibrillation
EP Europace, 2015
D.G. Wilson, E.R. Hyde, D.G. Wilson, S. Claridge, K.M.W Leong, …, S.A. Niederer, …, C. Roney, …
Posters 270Oversensing in subcutaneous implantable cardioverter-defibrillators71Early stimulation of the fast-conducting endocardium is the primary factor in reducing myocardial activation times for endocardial cardiac resynchronisation therap72The impact of age on outcomes in primary prevention icd recipients: a competing risks analysis73The effects of epicardial and endocardial pacing on the constituent waves of coronary flow: coronary resynchronisation74Manifestation of repolarisation and conduction abnormalities following exercise in concealed type 1 brugada75Delivering universal public access automated external defibrillators in the united kingdom: starting at the heart of the community76Under use of oral anticoagulation in new patients with atrial fibrillation: a clinical practice research datalink study77Complete extraction of abdominal pacing and icd leads- a unique case series78The impact of adjunctive complex fractionated atrial electrogram ablation and linear lesions on outcomes in persistent atrial fibrillation: a meta-analysis79Analysis of two novel risk calculators for the prediction of cardiac implantable electronic device infection80General anaesthesia improves the success rates of pulmonery vein isolation for paroxysmal atrial fibrillation ablation: Table 1
EP Europace, 2015
A. Crozier, C. M. Augustin, A. Neic, A. J. Prassl, M. Holler, …, M. J. Bishop, S. A. Niederer, …
Image-Based Personalization of Cardiac Anatomy for Coupled Electromechanical Modeling
Annals of Biomedical Engineering, 2015
Vinnie Bapat, Francesco Pirone, Stam Kapetanakis, Ronak Rajani, Steven Niederer
Factors influencing left ventricular outflow tract obstruction following a mitral valve‐in‐valve or valve‐in‐ring procedure, part 1
Catheterization and Cardiovascular Interventions, 2015
Sander Land, Steven A. Niederer
A Spatially Detailed Model of Isometric Contraction Based on Competitive Binding of Troponin I Explains Cooperative Interactions between Tropomyosin and Crossbridges
PLoS Computational Biology, 2015
Manav Sohal, Anoop Shetty, Steven Niederer, Angela Lee, Zhong Chen, Tom Jackson, Jonathan M. Behar, …
Mechanistic insights into the benefits of multisite pacing in cardiac resynchronization therapy: The importance of electrical substrate and rate of left ventricular activation
Heart Rhythm, 2015
Eoin R. Hyde, Jonathan M. Behar, Simon Claridge, Tom Jackson, Angela W.C. Lee, Espen W. Remme, …, Steven A. Niederer
Beneficial Effect on Cardiac Resynchronization From Left Ventricular Endocardial Pacing Is Mediated by Early Access to High Conduction Velocity Tissue
Circulation Arrhythmia and Electrophysiology, 2015
James Winter, Angela W.C. Lee, Steven Niederer, Michael J. Shattock
Vagal modulation of dispersion of repolarisation in the rabbit heart
Journal of Molecular and Cellular Cardiology, 2015
Martin Bishop, Ronak Rajani, Gernot Plank, Nicholas Gaddum, Gerry Carr-White, …, Steven Niederer
Three-dimensional atrial wall thickness maps to inform catheter ablation procedures for atrial fibrillation
EP Europace, 2015
Øyvind Nordbø, Arne B. Gjuvsland, Anders Nermoen, Sander Land, Steven Niederer, Pablo Lamata, …
Towards causally cohesive genotype–phenotype modelling for characterization of the soft-tissue mechanics of the heart in normal and pathological geometries
Journal of The Royal Society Interface, 2015
Anastasia Nasopoulou, Bojan Blazevic, Andrew Crozier, Wenzhe Shi, Anoop Shetty, …, Steven A. Niederer
Myocardial Stiffness Estimation: A Novel Cost Function for Unique Parameter Identification
Lecture notes in computer science, 2015
Cesare Corrado, Steven Williams, Henry Chubb, Mark O’Neill, Steven A. Niederer
Personalization of Atrial Electrophysiology Models from Decapolar Catheter Measurements
Lecture notes in computer science, 2015
Sander Land, Steve Niederer, Pablo Lamata
Estimation of Diastolic Biomarkers: Sensitiviy to Fibre Orientation
Lecture notes in computer science, 2014
Kristin Tøndel, Sander Land, Steven A. Niederer, Nicolas P. Smith
Quantifying inter‐species differences in contractile function through biophysical modelling
The Journal of Physiology, 2014
Sander Land, Steven A. Niederer, Pablo Lamata, Nicolas P. Smith
Improving the Stability of Cardiac Mechanical Simulations
IEEE Transactions on Biomedical Engineering, 2014
Simon Claridge, Zhong Chen, Tom Jackson, Eva Sammut, Manav Sohal, …, Steven Niederer, …
Current concepts relating coronary flow, myocardial perfusion and metabolism in left bundle branch block and cardiac resynchronisation therapy
International Journal of Cardiology, 2014
Alexandre Lewalle, Steven A. Niederer, Nicolas P. Smith
Species‐dependent adaptation of the cardiac Na+/K+ pump kinetics to the intracellular Na+ concentration
The Journal of Physiology, 2014
J. M. Aronsen, J. Skogestad, A. Lewalle, W. E. Louch, K. Hougen, M. K. Stokke, …, S. Niederer, …
Hypokalaemia induces Ca 2+ overload and Ca 2+ waves in ventricular myocytes by reducing Na + ,K + ‐ATPase α 2 activity
The Journal of Physiology, 2014
Sander Land, Steven A. Niederer, William E. Louch, Åsmund T. Røe, Jan Magnus Aronsen, Daniel J. Stuckey, …
Computational modeling of Takotsubo cardiomyopathy: effect of spatially varying β-adrenergic stimulation in the rat left ventricle
American Journal of Physiology-Heart and Circulatory Physiology, 2014
Øyvind Nordbø, Pablo Lamata, Sander Land, Steven Niederer, Jan M. Aronsen, William E. Louch, …
A computational pipeline for quantification of mouse myocardial stiffness parameters
Computers in Biology and Medicine, 2014
Pablo Lamata, Ramón Casero, Valentina Carapella, Steve A. Niederer, Martin J. Bishop, Jürgen E. Schneider, Peter Kohl, …
Images as drivers of progress in cardiac computational modelling
Progress in Biophysics and Molecular Biology, 2014
Manav Sohal, Simon G Duckett, Xiahai Zhuang, Wenzhe Shi, Matthew Ginks, …, Steven Niederer, …
A prospective evaluation of cardiovascular magnetic resonance measures of dyssynchrony in the prediction of response to cardiac resynchronization therapy
Journal of Cardiovascular Magnetic Resonance, 2014
Manav Sohal, Anoop Shetty, Steven Niederer, Zhong Chen, Tom Jackson, Eva Sammut, …
Delayed Trans-Septal Activation Results in Comparable Hemodynamic Effect of Left Ventricular and Biventricular Endocardial Pacing
Circulation Arrhythmia and Electrophysiology, 2014
Anoop K Shetty, Manav Sohal, Zhong Chen, Matthew R Ginks, Julian Bostock, …, Steven A Niederer, …
A comparison of left ventricular endocardial, multisite, and multipolar epicardial cardiac resynchronization: an acute haemodynamic and electroanatomical study
EP Europace, 2014
Kristin Tøndel, Steven A Niederer, Sander Land, Nicolas P Smith
Insight into model mechanisms through automatic parameter fitting: a new methodological framework for model development
BMC Systems Biology, 2014
Alexandre Lewalle, Steven Niederer, Nic Smith
Species-Specific Comparison of the Cardiac Sodium/Potassium Pump Based on a Minimal Biophysical Model
Biophysical Journal, 2014
William E. Louch, Sander Land, Steven A. Niederer
Strange bedfellows: biologists and mathematical modelers tie the knot on cardiomyocyte calcium homeostasis
Drug Discovery Today Disease Models, 2014
Pablo Lamata, Matthew Sinclair, Eric Kerfoot, Angela Lee, Andrew Crozier, Bojan Blazevic, …, Steve Niederer, …
An automatic service for the personalization of ventricular cardiac meshes
Journal of The Royal Society Interface, 2013
Steven Niederer
Regulation of Ion Gradients across Myocardial Ischemic Border Zones: A Biophysical Modelling Analysis
PLoS ONE, 2013
Sander Land, William E. Louch, Steven A. Niederer, Jan Magnus Aronsen, Geir Christensen, Ivar Sjaastad, …
Beta-Adrenergic Stimulation Maintains Cardiac Function in Serca2 Knockout Mice
Biophysical Journal, 2013
Eric Kerfoot, Pablo Lamata, Steve Niederer, Rod Hose, Jos Spaan, Nic Smith
Share and enjoy: anatomical models database—generating and sharing cardiovascular model data using web services
Medical & Biological Engineering & Computing, 2013
Sander Land, Steven A. Niederer, William E. Louch, Ole M. Sejersted, Nicolas P. Smith
Integrating multi-scale data to create a virtual physiological mouse heart
Interface Focus, 2013
Sander Land, Steven Niederer, D Stuckey, MB Sikkel, Siân E. Harding, Neil Smith
Computational modelling of stress (Takotsubo) cardiomyopathy
Proceedings of The Physiological Society, 2013
Pablo Lamata, Ishani Roy, Bojan Blazevic, Andrew Crozier, Sander Land, Steven A. Niederer, …
Quality Metrics for High Order Meshes: Analysis of the Mechanical Simulation of the Heart Beat
IEEE Transactions on Medical Imaging, 2012
Jiahe Xi, Pablo Lamata, Steven Niederer, Sander Land, Wenzhe Shi, Xiahai Zhuang, …
The estimation of patient-specific cardiac diastolic functions from clinical measurements
Medical Image Analysis, 2012
S. A. Niederer, S. Land, S. W. Omholt, N. P. Smith
Interpreting genetic effects through models of cardiac electromechanics
American Journal of Physiology-Heart and Circulatory Physiology, 2012
Steven Alexander Niederer, Pablo Lamata, Gernot Plank, Phani Chinchapatnam, Matt Ginks, …
Analyses of the Redistribution of Work following Cardiac Resynchronisation Therapy in a Patient Specific Model
PLoS ONE, 2012
Sander Land, Steven A. Niederer, Jan Magnus Aronsen, Emil K. S. Espe, Lili Zhang, William E. Louch, …
An analysis of deformation‐dependent electromechanical coupling in the mouse heart
The Journal of Physiology, 2012
O. Camara, M. Sermesant, P. Lamata, L. Wang, M. Pop, …, S. Niederer, …
Integration of different cardiac electrophysiological models into a single simulation pipeline
IEEE International Symposium on Biomedical Imaging (ISBI), 2012
Janos Magyar, Carmen E. Kiper, Gail Sievert, Weikang Cai, Geng-Xian Shi, …, Steven Niederer, …
Rem-GTPase regulates cardiac myocyte L-type calcium current
Channels, 2012
Liren Li, William E. Louch, Steven A. Niederer, Jan M. Aronsen, Geir Christensen, Ole M. Sejersted, …
Sodium Accumulation in SERCA Knockout-Induced Heart Failure
Biophysical Journal, 2012
P. Pathmanathan, M.O. Bernabeu, S.A. Niederer, D.J. Gavaghan, D. Kay
Computational modelling of cardiac electrophysiology: explanation of the variability of results from different numerical solvers
International Journal for Numerical Methods in Biomedical Engineering, 2012
S. A. Niederer, N. P. Smith
At the heart of computational modelling
The Journal of Physiology, 2012
Steven Niederer, Gernot Plank, Reza Rezavi, Aldo Rinaldi, Nic Smith
The Dependence of Clinical Metrics of Cardiac Function on Lead Position in Cardiac Resynchronization Therapy: A Biophysical Modeling Study
Springer eBooks, 2012
STEVEN A. NIEDERER, A.K. SHETTY, G. PLANK, J. BOSTOCK, R. RAZAVI, …
Biophysical Modeling to Simulate the Response to Multisite Left Ventricular Stimulation Using a Quadripolar Pacing Lead
Pacing and Clinical Electrophysiology, 2011
Steven A. Niederer, Eric Kerfoot, Alan P. Benson, Miguel O. Bernabeu, Olivier Bernus, …
Verification of cardiac tissue electrophysiology simulators using an N -version benchmark
Philosophical Transactions of the Royal Society A Mathematical Physical and Engineering Sciences, 2011
O. Camara, M. Sermesant, P. Lamata, L. Wang, M. Pop, …, S. Niederer, …
Inter-model consistency and complementarity: Learning from ex-vivo imaging and electrophysiological data towards an integrated understanding of cardiac physiology
Progress in Biophysics and Molecular Biology, 2011
Pablo Lamata, Steven Niederer, David Nordsletten, David C. Barber, Ishani Roy, D. Rod Hose, …
An accurate, fast and robust method to generate patient-specific cubic Hermite meshes
Medical Image Analysis, 2011
Jonathan Cooper, Gary R. Mirams, Steven A. Niederer
High-throughput functional curation of cellular electrophysiology models
Progress in Biophysics and Molecular Biology, 2011
S. Land, S. A. Niederer, N. P. Smith
Efficient Computational Methods for Strongly Coupled Cardiac Electromechanics
IEEE Transactions on Biomedical Engineering, 2011
Jiahe Xi, Pablo Lamata, Wenzhe Shi, Steven Niederer, Sander Land, Daniel Rueckert, …
An Automatic Data Assimilation Framework for Patient-Specific Myocardial Mechanical Parameter Estimation
Lecture notes in computer science, 2011
L. Li, W.E. Louch, S.A. Niederer, K.B. Andersson, G. Christensen, O.M. Sejersted, …
Calcium Dynamics in the Ventricular Myocytes of SERCA2 Knockout Mice: A Modeling Study
Biophysical Journal, 2011
Steven Niederer, Lawrence Mitchell, Nicolas Smith, Gernot Plank
Simulating Human Cardiac Electrophysiology on Clinical Time-Scales
Frontiers in Physiology, 2011
Steven A. Niederer, Gernot Plank, Phani Chinchapatnam, Matthew Ginks, Pablo Lamata, …
Length-dependent tension in the failing heart and the efficacy of cardiac resynchronization therapy
Cardiovascular Research, 2010
L. Li, S. A. Niederer, W. Idigo, Y. H. Zhang, P. Swietach, B. Casadei, …
A mathematical model of the murine ventricular myocyte: a data-driven biophysically based approach applied to mice overexpressing the canine NCX isoform
American Journal of Physiology-Heart and Circulatory Physiology, 2010
Martin Fink, Steven A. Niederer, Elizabeth M. Cherry, Flavio H. Fenton, Jussi T. Koivumäki, Gunnar Seemann, …
Cardiac cell modelling: Observations from the heart of the cardiac physiome project
Progress in Biophysics and Molecular Biology, 2010
Pablo Lamata, Steven Niederer, Gernot Plank, Nic Smith
Generic Conduction Parameters for Predicting Activation Waves in Customised Cardiac Electrophysiology Models
Lecture notes in computer science, 2010
Pablo Lamata, Steven Niederer, David Barber, David Norsletten, Jack Lee, Rod Hose, …
Personalization of Cubic Hermite Meshes for Efficient Biomechanical Simulations
Lecture notes in computer science, 2010
D.A. Nordsletten, S.A. Niederer, M.P. Nash, P.J. Hunter, N.P. Smith
Coupling multi-physics models to cardiac mechanics
Progress in Biophysics and Molecular Biology, 2009
Jack Lee, Steven Niederer, David Nordsletten, Ian Le Grice, Bruce Smail, David Kay, …
Coupling contraction, excitation, ventricular and coronary blood flow across scale and physics in the heart
Philosophical Transactions of the Royal Society A Mathematical Physical and Engineering Sciences, 2009
Steven A. Niederer, Nicolas P. Smith
The Role of the Frank–Starling Law in the Transduction of Cellular Work to Whole Organ Pump Function: A Computational Modeling Analysis
PLoS Computational Biology, 2009
S. A. Niederer, H. E. D. J. Ter Keurs, N. P. Smith
Modelling and measuring electromechanical coupling in the rat heart
Experimental Physiology, 2009
Steven A. Niederer, Nicolas P. Smith
The Role of the Frank-Starling Effect in the Transduction of Cellular Work into Whole Organ Pump Function: A Computational Modeling Analysis
Biophysical Journal, 2009
S. A. Niederer, M. Fink, D. Noble, N. P. Smith
A meta‐analysis of cardiac electrophysiology computational models
Experimental Physiology, 2009
Steven Niederer, Kawal Rhode, Reza Razavi, Nic Smith
The Importance of Model Parameters and Boundary Conditions in Whole Organ Models of Cardiac Contraction
Lecture notes in computer science, 2009
Jonna R. Terkildsen, Steven Niederer, Edmund J. Crampin, Peter Hunter, Nicolas P. Smith
Using Physiome standards to couple cellular functions for rat cardiac excitation–contraction
Experimental Physiology, 2008
D.S. Loiselle, E.J. Crampin, S.A. Niederer, N.P. Smith, C.J. Barclay
Energetic consequences of mechanical loads
Progress in Biophysics and Molecular Biology, 2008
S.A. Niederer, P. Swietach, D.A. Wilson, N.P. Smith, R.D. Vaughan-Jones
Measuring and Modeling Chloride-Hydroxyl Exchange in the Guinea-Pig Ventricular Myocyte
Biophysical Journal, 2007
Steven A. Niederer, Nicolas P. Smith
An improved numerical method for strong coupling of excitation and contraction models in the heart
Progress in Biophysics and Molecular Biology, 2007
Nicolas P. Smith, Edmund J. Crampin, Steven A. Niederer, James B. Bassingthwaighte, Daniel A. Beard
Computational biology of cardiac myocytes: proposed standards for the physiome
Journal of Experimental Biology, 2007
Steven A. Niederer, Nicolas P. Smith
A Mathematical Model of the Slow Force Response to Stretch in Rat Ventricular Myocytes
Biophysical Journal, 2007
David Nickerson, Steven Niederer, Carey Stevens, Martyn Nash, Peter Hunter
A Computational Model of Cardiac Electromechanics
Conference proceedings, 2006
S.A. Niederer, P.J. Hunter, N.P. Smith
A Quantitative Analysis of Cardiac Myocyte Relaxation: A Simulation Study
Biophysical Journal, 2005